4.0 Article

Evaluation of a Simple Low-cost Intervention to Empower People with CKD to Reduce Their Dietary Salt Intake: OxCKD1, a Multicenter Randomized Controlled Trial

Journal

KIDNEY360
Volume 4, Issue 7, Pages 890-898

Publisher

AMER SOC NEPHROLOGY
DOI: 10.34067/KID.0000000000000160

Keywords

CKD; chronic renal insufficiency; clinical nephrology; clinical trial; patient-centered care; randomized controlled trials

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The study aimed to evaluate a simple low-cost intervention to help people with CKD reduce their dietary salt intake. The results showed that after one month of the OxSalt care bundle intervention, dietary salt intake, assessed by 24-hour urine sodium excretion, decreased by 1.9 (+/- 2.9) g/d in the intervention group compared to 0.4 (+/- 2.7) g/d in the control group. Additionally, the intervention group continued to have a reduced salt intake to a lesser extent over the following year.
Background To evaluate the efficacy of a simple low-cost intervention to empower people with CKD to reduce their dietary salt intake. Methods A randomized controlled trial in primary and secondary care comparing the OxSalt care bundle intervention versus standard care for 1 month. Participants were people with CKD and an eGFR > 20 ml/min per 1.73 m(2) and were recruited from primary and secondary care. The primary outcome was a reduction in dietary salt intake, as assessed by 24-hour urinary sodium excretion, after 1 month of the intervention. Results Two hundred and one participants were recruited. Dietary salt intake, as assessed from 24-hour urine sodium excretion, fell by 1.9 (+/- 2.9) g/d in the intervention group compared with 0.4 (+/- 2.7) g/d in the control group (P < 0.001). Salt intake was still reduced to a lesser extent over the following year in the intervention group. Conclusions A short, low-cost, easily delivered intervention empowers people with CKD to reduce their dietary salt intake. Trial registration ClinicalTrials.gov NCT01552317.

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