Journal
NEW JOURNAL OF CHEMISTRY
Volume 40, Issue 9, Pages 7399-7406Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6nj00330c
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Funding
- NSFC [51503077, 21172063, 21472067]
- Taishan Scholar Foundation [TS 201511041]
- Natural Science Foundation of Shandong province [ZR2015PE001]
- University of Jinan [160082102]
- Open Project of State Key Laboratory for Supramolecular Structure and Materials [SKLSSM201207]
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Thiol-containing amino acids ( RSH) play a key role in maintaining the redox environment. In this work, we developed a novel dual-site two-photon ( TP) fluorescent RSH probe ( CA-TPP) for imaging mitochondrial RSH in living cells and mouse liver tissues. This probe exhibited rapid response and high TP photostability towards mitochondrial RSH. In particular, probe CA-TPP was capable of using TP fluorescence to track mitochondrial RSH over a long period.
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