Biometric linkage of longitudinally collected electronic case report forms and confirmation of subject identity: an open framework for ODK and related tools

Summary: This study aims to determine the effectiveness of a prophylactic vaccine during an Ebola virus outbreak in the Democratic Republic of the Congo. The participants, including adults and children aged 1 year and above, were offered a two-dose vaccine regimen. The study will also assess the safety and immune responses of the vaccine, and qualitative research will be conducted with participants or their parents/care providers.

Summary: The study utilized open-source tools like ODK to provide solutions for the use of an experimental vaccine, developed new features, and novel encryption protocols. It successfully managed data from over 280,000 study participants during epidemic response.