Journal
NEW ENGLAND JOURNAL OF MEDICINE
Volume 375, Issue 21, Pages 2051-2059Publisher
MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMoa1600931
Keywords
-
Categories
Funding
- Circulation Foundation
- United Kingdom National Institute for Health Research (NIHR)
- National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH)
- Circulation Foundation Surgeon Scientist Award
- NIHR Clinician Scientist Award [NIHR-CS-011-008]
- NHLBI [5R01HL105453-03]
- NIH [HL007734]
- Endologix
- Medtronic
- Gore
- Cordis
- British Heart Foundation [PG/13/98/30490] Funding Source: researchfish
- National Institute for Health Research [CL-2007-16-002, NIHR-CS-011-008] Funding Source: researchfish
Ask authors/readers for more resources
BACKGROUND Thresholds for repair of abdominal aortic aneurysms vary considerably among countries. METHODS We examined differences between England and the United States in the frequency of aneurysm repair, the mean aneurysm diameter at the time of the procedure, and rates of aneurysm rupture and aneurysm-related death. Data on the frequency of repair of intact (nonruptured) abdominal aortic aneurysms, in-hospital mortality among patients who had undergone aneurysm repair, and rates of aneurysm rupture during the period from 2005 through 2012 were extracted from the Hospital Episode Statistics database in England and the U.S. Nationwide Inpatient Sample. Data on the aneurysm diameter at the time of repair were extracted from the U.K. National Vascular Registry (2014 data) and from the U.S. National Surgical Quality Improvement Program (2013 data). Aneurysm-related mortality during the period from 2005 through 2012 was determined from data obtained from the Centers for Disease Control and Prevention and the U.K. Office of National Statistics. Data were adjusted with the use of direct standardization or conditional logistic regression for differences between England and the United States with respect to population age and sex. RESULTS During the period from 2005 through 2012, a total of 29,300 patients in England and 278,921 patients in the United States underwent repair of intact abdominal aortic aneurysms. Aneurysm repair was less common in England than in the United States (odds ratio, 0.49; 95% confidence interval [CI], 0.48 to 0.49; P<0.001), and aneurysm-related death was more common in England than in the United States (odds ratio, 3.60; 95% CI, 3.55 to 3.64; P<0.001). Hospitalization due to an aneurysm rupture occurred more frequently in England than in the United States (odds ratio, 2.23; 95% CI, 2.19 to 2.27; P<0.001), and the mean aneurysm diameter at the time of repair was larger in England (63.7 mm vs. 58.3 mm, P<0.001). CONCLUSIONS We found a lower rate of repair of abdominal aortic aneurysms and a larger mean aneurysm diameter at the time of repair in England than in the United States and lower rates of aneurysm rupture and aneurysm-related death in the United States than in England. (Funded by the Circulation Foundation and others.)
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available