Related references
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Article
Infectious Diseases
Joao Paulo Sales Oliveira-Correia et al.
Summary: There are currently 158 valid species of triatomines that can potentially transmit Trypanosoma cruzi, the causative agent of Chagas disease. Accurate taxonomic identification of triatomines is crucial as each species has different epidemiological implications. This study compared the terminal abdominal segments of females from five South American Triatoma species using scanning electron microscopy. The results revealed diagnostic characteristics for each species, with the dorsal view providing more valuable information. Similarities were observed among certain species, supporting previous research. Female genital characteristics were found to be reliable and useful for diagnosing the studied Triatoma species. Additional studies incorporating behavioral, morphological, and molecular data further supported the findings.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Infectious Diseases
Simone Kann et al.
Summary: Chagas Disease (CD) is highly prevalent among indigenous populations in the Sierra Nevada de Santa Marta, Colombia, with prevalence rates ranging from 43.6% to 67.4% in examined villages. The study found that ECG alterations in CD patients have the potential for early diagnosis. Although the ECG findings are unspecific, they should be considered as an indicator for CD screening and for early treatment if positive.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Infectious Diseases
Benjamin R. Bates et al.
Summary: The study conducted in-depth qualitative interviews with 33 residents in the Calvas Canton region of Ecuador to understand the barriers and facilitators to home reconstruction. The findings revealed that collective community efforts and social networks contribute to the intention of home reconstruction, while economic difficulties and the poor condition of existing homes are significant barriers. These findings are important for preventing Chagas disease and guiding community members and stakeholders in home reconstruction projects.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Infectious Diseases
Linda Vanesa Baldiviezo et al.
Summary: In this study, the bioinsecticidal activity and residual effect of a microencapsulation formulation of an entomopathogenic fungus (B. bassiana) were tested against pyrethroid-resistant Triatoma infestans nymphs. The microencapsulated fungus showed higher nymph mortality compared to the non-microencapsulated fungus and maintained conidial viability throughout the evaluation period. Alginate microencapsulation could serve as a cost-effective method for developing a bioinsecticide to reduce Chagas disease transmission.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Infectious Diseases
Rafaela Silva-Oliveira et al.
Summary: Two novel copper complex compounds have been found to inhibit Trypanosoma cruzi and have low toxicity on mammalian cells, making them promising candidates for further drug development.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Infectious Diseases
Pilar Rivadeneira-Barreiro et al.
Summary: This study aimed to determine the concentrations of acute phase proteins in dogs naturally infected with Trypanosoma cruzi and with or without seroreactivity to other vector-borne diseases. The results showed a reduction in the levels of paraoxonase-1 in Trypanosoma cruzi-seroreactive dogs, regardless of seroreactivity to other vector-borne diseases. Additionally, an increase in serum ferritin was observed in Trypanosoma cruzi-seroreactive dogs with seroreactivity to other vector-borne diseases. These findings suggest the presence of an oxidative stress response in Trypanosoma cruzi-seroreactive dogs without evident inflammation.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Infectious Diseases
Mary K. Lynn et al.
Summary: Congenital Chagas disease is a concern in El Salvador, particularly in the municipality of Jujutla. Older women and those familiar with someone infected are more likely to test positive for T. cruzi infection at the time of delivery. It is necessary to include T. cruzi in mandatory pregnancy screening programs.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Review
Infectious Diseases
Jose A. De Fuentes-Vicente et al.
Summary: Chagas disease is a complex and important tropical infection that primarily affects impoverished populations. The disease is caused by the protozoan parasite Trypanosoma cruzi, which is transmitted between insect vectors and mammals across the Americas. Despite significant advancements in understanding Chagas disease, there are still gaps in knowledge, making it crucial to continue conducting basic and applied research for more effective control strategies. This review aims to provide up-to-date information and highlight current research trends, serving as a starting point for beginners and facilitating further exploration.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Infectious Diseases
Natalia Velasquez-Ortiz et al.
Summary: A study in Colombia evaluated the parasite loads of 10 species of triatomines. The results showed that 82% of the triatomines were infected with Trypanosoma cruzi, with loads ranging from hundreds to millions of equivalent parasites per milliliter. Additionally, species whose role as vectors is still unknown were found with high loads of parasites.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2022)
Review
Cardiac & Cardiovascular Systems
Natalia Giraldo Echavarria et al.
Summary: Chagas disease is a tropical vector-borne infection caused by the parasite Trypanosoma cruzi, endemic in South and Central America but increasingly becoming a burden in the United States and Europe due to human migration. Most patients are asymptomatic during the acute phase, with around 30% progressing to detectable organ damage mainly affecting the cardiovascular and digestive systems in the chronic symptomatic phase, which can lead to Chagas cardiomyopathy, a leading cause of nonischemic cardiomyopathy in Latin America. Treatment during the parasitic infection is possible, but efficacy during the advanced chronic symptomatic phase remains uncertain. Further studies are needed to improve clinical outcomes and refine treatment recommendations.
CURRENT PROBLEMS IN CARDIOLOGY
(2021)
Review
Pharmacology & Pharmacy
Aline A. Zuma et al.
Summary: Chagas disease is a Neglected Tropical Disease affecting around 6-7 million people worldwide, predominantly in Latin America. Current treatments, benznidazole and nifurtimox, have limited effectiveness and can cause side effects, especially in the chronic phase. Studies have shown potential new drugs with equivalent or superior efficacy to benznidazole, highlighting the need for further research to improve treatment options.
CURRENT PHARMACEUTICAL DESIGN
(2021)
Article
Infectious Diseases
Leandro S. Sangenito et al.
TROPICAL MEDICINE AND INFECTIOUS DISEASE
(2020)
Review
Public, Environmental & Occupational Health
Karita Claudia Freitas Lidani et al.
FRONTIERS IN PUBLIC HEALTH
(2019)
