CT-based online adaptive radiotherapy improves target coverage and organ at risk (OAR) avoidance in stereotactic body radiation therapy (SBRT) for prostate cancer

Article Oncology

Propensity-Weighted Survival Analysis of SBRT vs. Conventional Radiotherapy in Unfavorable Intermediate-Risk Prostate Cancer

Neal Andruska et al.

Summary: In patients with unfavorable intermediate-risk prostate cancer, the use of SBRT was associated with significantly longer survival compared to longer courses of radiotherapy. This study provides support for the use of SBRT in this patient population.

CLINICAL GENITOURINARY CANCER (2022)

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Article Radiology, Nuclear Medicine & Medical Imaging

Varian ethos online adaptive radiotherapy for prostate cancer: Early results of contouring accuracy, treatment plan quality, and treatment time

Mikel Byrne et al.

Summary: The Varian Ethos system enables online adaptive treatments using AI and deformable image registration, automating anatomical contouring and plan optimization processes to improve dosimetry in prostate radiotherapy.

JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS (2022)

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Article Oncology

Prostate-Only Versus Whole-Pelvic Radiation Therapy in High-Risk and Very High-Risk Prostate Cancer (POP-RT): Outcomes From Phase III Randomized Controlled Trial

Vedang Murthy et al.

Summary: In high-risk, locally advanced prostate cancer patients, prophylactic pelvic irradiation showed improved biochemical failure-free survival and disease-free survival compared to prostate-only radiotherapy, though overall survival did not appear to differ significantly.

JOURNAL OF CLINICAL ONCOLOGY (2021)

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Article Oncology