Evaluating the Feasibility of Hydrogel-Based Neural Cell Sprays

Neurological injuries have poor prognoses with serious clinical sequelae. Stem cell transplantation enhances neural repair but is hampered by low graft survival (ca. 80%) and marker expression/proliferative potential of hydrogel-sprayed astrocytes was retained. Combining a cell spray format with polymer encapsulation technologies could form the basis of a non-invasive graft delivery method, offering potential advantages over current cell delivery approaches.

Automated summary

Neurological injuries often lead to serious clinical consequences, but stem cell transplantation can enhance neural repair. However, the current cell delivery methods have limitations. Researchers propose combining cell spray technology with polymer encapsulation to develop a non-invasive graft delivery method.