☆ 4.5 Article

Nanotherapeutics with immunoregulatory functions for the treatment of bacterial infection

Biomaterials Research (2023)

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Summary: Given the challenges of bacterial resistance and biofilm protection, photothermal therapy (PTT)-derived multimodal synergistic treatments have emerged as a promising approach to combat bacterial infections. By combining PTT with chemotherapy, photo-dynamic/catalytic therapy, immunotherapy, and sonodynamic therapy, enhanced bactericidal activity can be achieved while minimizing potential side effects.

CHEMICAL SOCIETY REVIEWS (2021)

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Article Chemistry, Multidisciplinary

In situ injection of dual-delivery PEG based MMP-2 sensitive hydrogels for enhanced tumor penetration and chemo-immune combination therapy

Jianqin Yan et al.

Summary: The study utilized a nuclear-targeted tetrahedral DNA nanostructure to construct a delivery system combining chemotherapy and immunotherapy, achieving successful treatment of breast cancer with significant efficacy demonstrated in both in vivo and in vitro experiments.

NANOSCALE (2021)

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Article Chemistry, Physical

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

Byungji Kim et al.

Summary: Immunotherapy offers a broad-spectrum therapeutic solution against bacterial infections by deterring antibiotic-resistant strains and minimizing the need for new pathogen-specific antibiotics. Targeted nanoparticles loaded with siRNA against the Irf5 gene show promise in improving therapeutic outcomes by effectively silencing the gene in activated macrophages.

NANOSCALE HORIZONS (2021)

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Review Materials Science, Biomaterials

Photothermal bactericidal surfaces: killing bacteria using light instead of biocides

Yi Zou et al.

Summary: Endowing synthetic materials with bactericidal activity can effectively prevent bacterial colonization and biofilm formation, while photothermal bactericidal surfaces have emerged as a promising alternative for combating surface-attached bacteria, offering broad-spectrum sterilization ability and no drug resistance.

BIOMATERIALS SCIENCE (2021)

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Article Chemistry, Multidisciplinary

Near-Infrared Light-Triggered Nitric-Oxide-Enhanced Photodynamic Therapy and Low-Temperature Photothermal Therapy for Biofilm Elimination

Zhang Yuan et al.

ACS NANO (2020)

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Article Chemistry, Multidisciplinary

Fe3O4@TiO2-Laden Neutrophils Activate Innate Immunity via Photosensitive Reactive Oxygen Species Release

Peng Zhang et al.

NANO LETTERS (2020)

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Article Multidisciplinary Sciences

Biofilm Microenvironment-Responsive Nanotheranostics for Dual-Mode Imaging and Hypoxia-Relief-Enhanced Photodynamic Therapy of Bacterial Infections

Weijun Xiu et al.

RESEARCH (2020)

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Article Chemistry, Multidisciplinary

Near-Infrared Light Triggered Phototherapy and Immunotherapy for Elimination of Methicillin-Resistant Staphylococcus aureus Biofilm Infection on Bone Implant

Yuan Li et al.

ACS NANO (2020)

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Article Engineering, Environmental

Synergistic chemotherapy, physiotherapy and photothermal therapy against bacterial and biofilms infections through construction of chiral glutamic acid functionalized gold nanobipyramids

Min Zhang et al.

CHEMICAL ENGINEERING JOURNAL (2020)

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Article Chemistry, Multidisciplinary

Space-Selective Chemodynamic Therapy of CuFe5O8 Nanocubes for Implant-Related Infections

Geyong Guo et al.

ACS NANO (2020)

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Article Chemistry, Multidisciplinary

Photosensitizer-Modified MnO2 Nanoparticles to Enhance Photodynamic Treatment of Abscesses and Boost Immune Protection for Treated Mice

Chenya Wang et al.

SMALL (2020)

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Review Materials Science, Multidisciplinary

Surface Modified Techniques and Emerging Functional Coating of Dental Implants

Heng Dong et al.

COATINGS (2020)

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Review Materials Science, Biomaterials

Recent advances in pH-responsive nanomaterials for anti-infective therapy

Xinyi Lv et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

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Article Materials Science, Biomaterials

An acidity-responsive polyoxometalate with inflammatory retention for NIR-II photothermal-enhanced chemodynamic antibacterial therapy

Yunhao Shi et al.

BIOMATERIALS SCIENCE (2020)

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Article Immunology

The importance of exosomal PDL1 in tumour immune evasion

Dhouha Daassi et al.

NATURE REVIEWS IMMUNOLOGY (2020)

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Article Chemistry, Multidisciplinary

Sono-Immunotherapeutic Nanocapturer to Combat Multidrug-Resistant Bacterial Infections

Xin Pang et al.

ADVANCED MATERIALS (2019)

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Article Robotics

Catalytic antimicrobial robots for biofilm eradication

Geelsu Hwang et al.

SCIENCE ROBOTICS (2019)

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Article Microbiology

Development of a Gold Nanoparticle Vaccine against Enterohemorrhagic Escherichia coli O157:H7

Javier I. Sanchez-Villamil et al.

MBIO (2019)

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Article Multidisciplinary Sciences

Endogenous stimulus-powered antibiotic release from nanoreactors for a combination therapy of bacterial infections

Yang Wu et al.

NATURE COMMUNICATIONS (2019)

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Review Chemistry, Multidisciplinary

Local biomaterials-assisted cancer immunotherapy to trigger systemic antitumor responses

Qian Chen et al.

CHEMICAL SOCIETY REVIEWS (2019)

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Article Infectious Diseases

Protection Against Lethal Multidrug-Resistant Bacterial Infections Using Macrophage Cell Therapy

Robert Tacke et al.

INFECTIOUS MICROBES & DISEASES (2019)

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Review Chemistry, Multidisciplinary

Recent advances in nanomaterial-based synergistic combination cancer immunotherapy

Wei Sang et al.

CHEMICAL SOCIETY REVIEWS (2019)

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Review Biotechnology & Applied Microbiology

Host-directed therapies for bacterial and viral infections

Stefan H. E. Kaufmann et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

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Article Biochemistry & Molecular Biology

Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection

Felipe A. Pinho-Ribeiro et al.

CELL (2018)

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Hydrogen Sulfide in Physiology and Pathogenesis of Bacteria and Viruses

Virender Kumar Pal et al.

IUBMB LIFE (2018)

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Article Multidisciplinary Sciences

Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus

Byungji Kim et al.

NATURE COMMUNICATIONS (2018)

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Review Immunology

Immune checkpoint blockade in infectious diseases

Michelle N. Wykes et al.

NATURE REVIEWS IMMUNOLOGY (2018)

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Article Multidisciplinary Sciences

Nanoparticle curcumin ameliorates experimental colitis via modulation of gut microbiota and induction of regulatory T cells

Masashi Ohno et al.

PLOS ONE (2017)

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Article Microbiology

Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function

Jason H. Yang et al.

CELL HOST & MICROBE (2017)

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Article Chemistry, Multidisciplinary

In Situ Capture of Bacterial Toxins for Antivirulence Vaccination

Xiaoli Wei et al.

ADVANCED MATERIALS (2017)

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Liposome-based intranasal delivery of lipopeptide vaccine candidates against group A streptococcus

Khairunnisa Abdul Ghaffar et al.

ACTA BIOMATERIALIA (2016)

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Article Chemistry, Multidisciplinary

Nanoparticle-Based Antivirulence Vaccine for the Management of Methicillin-Resistant Staphylococcus aureus Skin Infection

Fei Wang et al.

ADVANCED FUNCTIONAL MATERIALS (2016)

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Aryl hydrocarbon receptor influences nitric oxide and arginine production and alters M1/M2 macrophage polarization

Samantha Climaco-Arvizu et al.

LIFE SCIENCES (2016)

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The Immune Battle against Helicobacter pylori Infection: NO Offense

Alain P. Gobert et al.

TRENDS IN MICROBIOLOGY (2016)

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Future challenges in the in vitro and in vivo evaluation of biomaterial biocompatibility

James M. Anderson

REGENERATIVE BIOMATERIALS (2016)

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Article Chemistry, Multidisciplinary

Modulating Antibacterial Immunity via Bacterial Membrane-Coated Nanoparticles

Weiwei Gao et al.

NANO LETTERS (2015)

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Reactive Oxygen Species in Inflammation and Tissue Injury

Manish Mittal et al.

ANTIOXIDANTS & REDOX SIGNALING (2014)

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Molecular mechanisms that influence the macrophage M1-M2 polarization balance

Nan Wang et al.

FRONTIERS IN IMMUNOLOGY (2014)

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TLR agonists as modulators of the innate immune response and their potential as agents against infectious disease

Edin J. Mifsud et al.

FRONTIERS IN IMMUNOLOGY (2014)

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Biofilm switch and immune response determinants at early stages of infection

Jaione Valle et al.

TRENDS IN MICROBIOLOGY (2013)

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Photodynamic therapy induces an immune response against a bacterial pathogen

Ying-Ying Huang et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2012)

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Photodynamic Therapy Can Induce a Protective Innate Immune Response against Murine Bacterial Arthritis via Neutrophil Accumulation

Masamitsu Tanaka et al.

PLOS ONE (2012)

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Article Dermatology

Photodynamic Therapy for Infections: Clinical Applications

Gitika B. Kharkwal et al.

LASERS IN SURGERY AND MEDICINE (2011)

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Review Biochemical Research Methods

Antibodies for the treatment of bacterial infections: current experience and future prospects

Christopher Bebbington et al.

CURRENT OPINION IN BIOTECHNOLOGY (2008)

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The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis

Andrea M. Cooper et al.

IMMUNOLOGICAL REVIEWS (2008)

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Interleukin-17 as an effector molecule of innate and acquired immunity against infections

Goro Matsuzaki et al.

MICROBIOLOGY AND IMMUNOLOGY (2007)

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Anthrax toxins: a paradigm of bacterial immune suppression

Cosima T. Baldari et al.

TRENDS IN IMMUNOLOGY (2006)

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Passive antibody therapy for infectious diseases

A Casadevall et al.

NATURE REVIEWS MICROBIOLOGY (2004)

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Opinion - Can innate immunity be enhanced to treat microbial infections?

BB Finlay et al.

NATURE REVIEWS MICROBIOLOGY (2004)

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Implant infections: a haven for opportunistic bacteria

JM Schierholz et al.

JOURNAL OF HOSPITAL INFECTION (2001)

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The Toll receptor family and microbial recognition

R Medzhitov et al.

TRENDS IN MICROBIOLOGY (2000)

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