☆ 4.1 Article

Comparative study of bio-functional profile and bioactivities of polysaccharides from Ganoderma lucidum and Ganoderma neo- japonicum

BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY (2023)

Related references

Note: Only part of the references are listed.

Article Plant Sciences

Ganoderma lucidum polysaccharide inhibits HSC activation and liver fibrosis via targeting inflammation, apoptosis, cell cycle, and ECM-receptor interaction mediated by TGF-β/Smad signaling

Chaojie Chen et al.

Summary: This study provides the first evidence that Ganoderma lucidum polysaccharide (GLP) could be a promising dietary strategy for treating liver fibrosis, which protects against liver fibrosis and hepatic stellate cell (HSC) activation through targeting inflammation, apoptosis, cell cycle, and extracellular matrix-receptor interactions mediated by the TGF-beta/Smad signaling pathway.

PHYTOMEDICINE (2023)

Add to Collection

Article Horticulture

Multivariate comparative analysis of chemical constituent changes and antioxidant properties of polysaccharides in ribes stenocarpum maxim. at different maturity stages on the Qinghai-Tibet Plateau

Xinyue Liang et al.

Summary: This study conducted a detailed chemical analysis of the Ribes stenocarpum Maxim. fruits in the Qinghai-Tibet Plateau and found significant differences in chemical composition at different stages of maturity. The study also revealed that the polysaccharide structure and monosaccharide composition have important impacts on antioxidant activity, with immature and over-mature fruits exhibiting higher antioxidant activity.

SCIENTIA HORTICULTURAE (2023)

Add to Collection

Article Food Science & Technology

Molecular mechanisms of the chemical constituents from anti-inflammatory and antioxidant active fractions of Ganoderma neo-japonicum Imazeki

Rui-rui Zhang et al.

Summary: In this study, 47 triterpenoids were identified in the crude extracts of Ganoderma neo-japonicum using UHPLC-Triple TOF-MS/MS. Fraction (c) showed the strongest bioactivity in terms of antioxidant and anti-inflammatory effects. It was found that Fr. (c) reduced the levels of inflammatory cytokines and reactive oxygen species in macrophages, and this effect was mediated through the activation of the Nrf2/HO-1 pathway and inactivation of the NF-kappa B pathway. These findings suggest that Fr. (c) of G. neo-japonicum could be a potential functional food for health and longevity.

CURRENT RESEARCH IN FOOD SCIENCE (2023)

Add to Collection

Article Multidisciplinary Sciences

In vitro gastrointestinal digestion of Lentinus squarrosulus powder and impact on human fecal microbiota

Francis Ayimbila et al.

Summary: This study examined the nutritional composition, digestion, and colonic fermentation of Lentinus squarrosulus powder (LP), finding that it has the potential to improve gut health.

SCIENTIFIC REPORTS (2022)

Add to Collection

Article Polymer Science

Polysaccharides from Basidiocarps of the Polypore Fungus Ganoderma resinaceum: Isolation and Structure

Roman Bleha et al.

Summary: This study focused on the isolation and structural characterization of polysaccharides from a basidiocarp of polypore fungus Ganoderma resinaceum. Different extraction methods were used to obtain polysaccharide fractions, and their purity, composition, and structure were characterized using various analysis techniques. The main polysaccharides identified were branched O-2-beta-d-mannosyl-(1 -> 6)-alpha-d-galactan and highly branched (1 -> 3)(1 -> 4)(1 -> 6)-beta-d-glucan in the cold water and hot water extracts, respectively.

POLYMERS (2022)

Add to Collection

Article Chemistry, Applied

A new anti-tumor cytotoxic triterpene from Ganoderma lucidum

Liping Cao et al.

Summary: Ganoderma lucidum, a traditional medicinal fungus in China, has been found to possess a new triterpene compound that shows moderate anti-tumor activities, possibly inducing apoptosis through the p53/caspase-3 pathway.

NATURAL PRODUCT RESEARCH (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Optimization of Ultrasonic-Assisted Extraction of Total Flavonoids from Abrus Cantoniensis (Abriherba) by Response Surface Methodology and Evaluation of Its Anti-Inflammatory Effect

En-Yun Wu et al.

Summary: Abrus cantoniensis is a Chinese herbal medicine known for its heat-clearing, detoxifying, and liver pain relieving properties. Modern pharmacological studies have shown that its flavonoids have important biological activities such as anti-inflammatory, antibacterial, and antioxidant effects. By optimizing the ultrasonic extraction process, researchers found that ATF has significant anti-inflammatory effects both in vitro and in vivo.

MOLECULES (2022)

Add to Collection

Article Food Science & Technology

Polysaccharide extracts from mycelia of Ganoderma australe: effect on dendritic cell immunomodulation and antioxidant activity

A. L. Gallo et al.

Summary: Ganoderma australe, a species of fungi, has inner-polysaccharides (IPS) that modulate immune response and have antioxidant activity. In this study, the effects of the IPS on dendritic cell activation and maturation, as well as its antioxidant activity, were assessed. The chemical composition of the IPS extracts varied, with glucose, mannose, and galactose being the predominant components. The IPS from mycelia growing in M1 significantly increased the expression levels of MHC II and CD86, while the IPS from mycelia growing in M2 showed significant antioxidant activity, possibly due to the presence of phenolic compounds. This study highlights the potential immunomodulatory and antioxidant effects of the aqueous extracts of mycelial polysaccharides from G. australe.

JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION (2022)

Add to Collection

Article Food Science & Technology

Chitooligosaccharide Conjugates Prepared Using Several Phenolic Compounds via Ascorbic Acid/H2O2 Free Radical Grafting: Characteristics, Antioxidant, Antidiabetic, and Antimicrobial Activities

Ajay Mittal et al.

Summary: In this study, polyphenol (PPN) conjugates with different PPNs and various concentrations of chitooligosaccharide (COS) were prepared and characterized. The results showed that COS-catechin (COS-CAT) had the highest conjugation efficiency and total phenolic content. In terms of antioxidant and antimicrobial activities, COS-CAT exhibited the best performance. Furthermore, COS-CAT showed the highest inhibitory activity against digestive enzymes and antimicrobial activity.

FOODS (2022)

Add to Collection

Review Food Science & Technology

Nutritional Profile and Health Benefits of Ganoderma lucidum Lingzhi, Reishi, or Mannentake as Functional Foods: Current Scenario and Future Perspectives

Aly Farag El Sheikha

Summary: Ganoderma lucidum, with a long history of medicinal use, has potential as an antiviral medicine and is widely used in the nutraceutical and cosmetics industries. Further research on its biotherapeutic components is needed to ensure safety and effectiveness, and to promote the development of commercial functional foods.

FOODS (2022)

Add to Collection

Article Chemistry, Physical

Characterization of nanofiber composite membrane for high water flux and antibacterial properties

Hamouda M. Mousa et al.

Summary: This study developed a facile method of alkaline treatment for nanostructured membranes, which exhibited superhydrophilic property and antibacterial activity. The membranes showed promising results in water filtration and treatment.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Anticancer and Antioxidant Activities in Ganoderma lucidum Wild Mushrooms in Poland, as Well as Their Phenolic and Triterpenoid Compounds

Joanna Kolniak-Ostek et al.

Summary: This study assessed the anti-cancer and antioxidant properties of Ganoderma lucidum fruiting body and identified bioactive compounds in its extracts. The extracts showed significant antiproliferative activity against various cancer cell lines, and contained triterpenoids and polyphenols as the main bioactive compounds.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection

Article Food Science & Technology

Antioxidant, hypoglycemic and protection of acute liver injury activities of Ganoderma lucidum spore water extract

Long Zhang et al.

Summary: This study identified the chemical composition of sporoderm-broken Ganoderma lucidum spore water extract (BGLWE) and found that it exhibits antioxidant and hypoglycemic activities. BGLWE also showed protective effects against acute liver injury.

JOURNAL OF FUNCTIONAL FOODS (2022)

Add to Collection

Review Biochemistry & Molecular Biology

How Microbes Evolved to Tolerate Oxygen

Maryam Khademian et al.

Summary: Ancient microbes developed biochemical mechanisms and core metabolic pathways on an anoxic Earth, but had to evolve defensive tactics to combat the damaging effects of oxygen and reactive oxygen species (ROS) later on. Recent studies have identified enzymes targeted by ROS and revealed various protective strategies to enhance scavenging systems, shedding light on a more comprehensive and surprising understanding of oxygen toxicity.

TRENDS IN MICROBIOLOGY (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Structure and chain conformation of bioactive β-D-glucan purified from water extracts of Ganoderma lucidum unbroken spores

Yanfang Liu et al.

Summary: Two polysaccharide fractions (GLSB50 and GLSB70) were obtained from Ganoderma lucidum spores, with GLSB50 showing better activity in stimulating humoral immune responses in immunosuppressed mice. A novel β-D-glucan (GLSB50A-III-1) was purified from GLSB50, with structural analysis revealing it mainly consisted of β-D-glucose residues.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Add to Collection

Article

Structural characteristics and bioactive properties of water-soluble polysaccharide from Lentinus squarrosulus

Francis Ayimbila et al.

Bioactive Carbohydrates and Dietary Fibre (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Ganoderma lucidum: A potential source to surmount viral infections through β-glucans immunomodulatory and triterpenoids antiviral properties

Md Faruque Ahmad et al.

Summary: Ganoderma lucidum polysaccharides and triterpenoids are the major bioactive compounds with immunomodulatory and antiviral properties, playing a potential role in preventing and treating various diseases by enhancing the immune system and producing immune responses.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Add to Collection

Review Biotechnology & Applied Microbiology

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

Henry Jay Forman et al.

Summary: Oxidative stress plays a role in various diseases, and understanding the mechanisms behind antioxidants and how to enhance antioxidant defences may lead to greater pharmacological success.

NATURE REVIEWS DRUG DISCOVERY (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Towards the sustainable discovery and development of new antibiotics

Marcus Miethke et al.

Summary: There is a growing demand for novel antimicrobials to treat infections caused by multidrug-resistant bacterial pathogens, but there is currently a lack of investment in this field. New agents with innovative chemistry and modes of action are urgently needed to combat the public health threat posed by antimicrobial resistance. The consortium proposes short-term and long-term solutions to overcome urgent limitations in research and funding, aiming to bridge the gap between academic, industrial, and political stakeholders to improve the ability to discover and develop new antibiotics.

NATURE REVIEWS CHEMISTRY (2021)

Add to Collection

Review Plant Sciences

The beneficial effects of Ganoderma lucidum on cardiovascular and metabolic disease risk

Sze Wa Chan et al.

Summary: This review examines the effects of Ganoderma lucidum on major risk factors for cardiometabolic disease, showing potential benefits such as antioxidative, antihypertensive, hypoglycaemic, lipid-lowering, and anti-inflammatory properties in in vitro and in vivo studies. However, clinical trials have shown inconsistent results, indicating the need for further large controlled studies to clarify the potential health benefits of G. lucidum preparations standardized by known active components in the prevention and treatment of cardiometabolic disease.

PHARMACEUTICAL BIOLOGY (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Molecular mechanisms of bioactive polysaccharides from Ganoderma lucidum (Lingzhi), a review

Jiahui Lu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Extraction optimization, characterization and the antioxidant activities in vitro and in vivo of polysaccharide from Pleurotus ferulae

Wei Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Add to Collection

Review Biochemistry & Molecular Biology

Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It

Zeinab Breijyeh et al.

MOLECULES (2020)

Add to Collection

Review Food Science & Technology

Macrofungi: A review of cultivation strategies, bioactivity, and application of mushrooms

Hongyun Lu et al.

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY (2020)

Add to Collection

Article Cell Biology

In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19

Xiao-Jin Zhang et al.

CELL METABOLISM (2020)

Add to Collection

Article Agricultural Engineering

Antibacterial activity and mechanism of green tea polysaccharide conjugates against Escherichia coli

Yin Zhou et al.

INDUSTRIAL CROPS AND PRODUCTS (2020)

Add to Collection

Review Plant Sciences

Ganoderma lucidum: A rational pharmacological approach to surmount cancer

Md Faruque Ahmad

JOURNAL OF ETHNOPHARMACOLOGY (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Structural characterization and immunomodulatory activity of a polysaccharide from Eurotium cristatum

Haohan Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Add to Collection

Article Chemistry, Applied

In vitro antioxidant activity of Kyoho grape extracts in DPPH• and ABTS• assays: Estimation methods for EC50 using advanced statistical programs

Kandi Sridhar et al.

FOOD CHEMISTRY (2019)

Add to Collection

Article Biochemistry & Molecular Biology

Comparison on characterization and antioxidant activity of polysaccharides from Ganoderma lucidum by ultrasound and conventional extraction

Qiaozhen Kang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Add to Collection

Article Food Science & Technology

Bio compounds of edible mushrooms: in vitro antioxidant and antimicrobial activities

Fabiane Bach et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2019)

Add to Collection

Article Food Science & Technology

High-intensity ultrasound processing of kiwifruit juice: Effects on the ascorbic acid, total phenolics, flavonoids and antioxidant capacity

Jin Wang et al.

LWT-FOOD SCIENCE AND TECHNOLOGY (2019)

Add to Collection

Review Chemistry, Medicinal

The Antioxidant Activity of Polysaccharides Derived from Marine Organisms: An Overview

Qiwu Zhong et al.

MARINE DRUGS (2019)

Add to Collection

Article Chemistry, Applied

Characterization, antioxidant and hypoglycemic activities of degraded polysaccharides from blackcurrant (Ribes nigrum L.) fruits

Yaqin Xu et al.

FOOD CHEMISTRY (2018)

Add to Collection

Article Biochemistry & Molecular Biology

Antioxidant and antimicrobial potential of polysaccharides sequentially extracted from Polygonatum cyrtonema Hua

Ling Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Add to Collection

Review Biochemistry & Molecular Biology

Antitumour, Antimicrobial, Antioxidant and Antiacetylcholinesterase Effect of Ganoderma Lucidum Terpenoids and Polysaccharides: A Review

Darija Cor et al.

MOLECULES (2018)

Add to Collection

Article Biochemistry & Molecular Biology

Quorum sensing molecule-farnesol increased the production and biological activities of extracellular polysaccharide from Trametes versicolor

Ke-Feng Wang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

Add to Collection

Review Food Science & Technology

Functional foods based on extracts or compounds derived from mushrooms

Filipa S. Reis et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2017)

Add to Collection

Article Microbiology

The Antibacterial Activity of Coriolus versicolor Methanol Extract and Its Effect on Ultrastructural Changes of Staphylococcus aureus and Salmonella Enteritidis

Danka Matijasevic et al.

FRONTIERS IN MICROBIOLOGY (2016)

Add to Collection

Article Chemistry, Applied

Effects of culture conditions on monosaccharide composition of Ganoderma lucidum exopolysaccharide and on activities of related enzymes

Lin Peng et al.

CARBOHYDRATE POLYMERS (2015)

Add to Collection

Article Biochemistry & Molecular Biology

Structural analysis and antioxidant activities of polysaccharide isolated from Jinqian mushroom

Yong Liu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)

Add to Collection

Article Cardiac & Cardiovascular Systems

Natural products as a robust source of new drugs and drug leads: Past successes and present day issues

Gilbert M. Rishton

AMERICAN JOURNAL OF CARDIOLOGY (2008)

Add to Collection

Article Chemistry, Applied

Phenolic contents and antioxidant activities of bitter gourd (Momordica charantia L.) leaf, stem and fruit fraction extracts in vitro

Jittawan Kubola et al.

FOOD CHEMISTRY (2008)

Add to Collection

© Peeref 2019-2024. All rights reserved.