Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 357, Issue 4, Pages 753-760Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201400721
Keywords
gold; heterogeneous catalyst; nanoparticles; N-formylation; quinolines; transfer hydrogenation
Categories
Funding
- National Natural Science Foundation of China [21273044]
- Research Fund for the Doctoral Program of Higher Education [20120071110011]
- Science & Technology Commission of Shanghai Municipality [08DZ2270500, 12ZR1401500]
Ask authors/readers for more resources
Single phase rutile titania supported gold nanoparticles (Au/TiO2-R) are found to be efficient and versatile catalysts for chemo-and regioselective transfer hydrogenation of quinoline derivatives to 1,2,3,4-tetrahydroquinolines (THQs) using formic acid (FA) as a safe and convenient hydrogen source under mild conditions. The activity and chemoselectivity of the Au/TiO2-R catalyst towards THQs is excellent, with a substrate to catalyst ratio (S/C) of 1000 being feasible. Furthermore, a straightforward and selective route to N-formyltetrahydroquinolines (FTHQ) directly from quinoline compounds and FA by one-pot, gold-catalyzed reductive N-formylation protocol is also established.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available