Journal
NEUROLOGY
Volume 87, Issue 9, Pages S59-S66Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/WNL.0000000000002824
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Funding
- MS Cure Fund
- Danish MS Society
- German MS Society
- Italian MS Association
- MS International Federation
- MS Research Foundation (Netherlands)
- National MS Society (USA)
- Swiss MS Society
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Neuromyelitis optica (NMO) is a severe autoimmune disease of the CNS characterized by recurrent inflammatory events primarily involving the optic nerves and spinal cord. NMO is infrequent in children, but early recognition is important to start adequate treatment. In this article, we review the evolving diagnostic criteria of NMO and provide an update on the clinical and neuroimaging spectrum of the disorder in pediatric patients, including current knowledge on immunopathogenesis and treatment recommendations for children with NMO.
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