Malignes Melanom und Adipositas: eine & Uuml;bersichtsarbeit

Introduction The incidence of obesity continues to increase worldwide. Obesity is discussed as a potential risk factor for various types of cancer including malignant melanoma. This review presents the evidence for the association between obesity and malignant melanoma.Methods Selective literature search. Results Although several explanatory approaches for the association between obesity and malignant melanoma exist, these are currently not fully understood and remain subject of research. The evidence on the association between obesity and melanoma outcomes for patients without systemic therapy is low. For patients with systemic therapy existing evidence points to a protective effect of immuno-and targeted therapies. Conclusion Overall, current evidence is insufficient to conclude whether obesity has an independent protective effect or is a risk factor for the development of malignant melanoma. Further research is needed to assess this potential association in greater depth.

Automated summary

The association between obesity and malignant melanoma is not fully understood and requires further research to assess its potential.