Drug repurposing of Mito-Atovaquone for cancer treatment

Repurposing of approved drugs in a new strategy to combat cancer that leads to savings in time and investment. Atovaquone is a US FDA approved drug for treatment of Pneumocystis carinii pneumonia and malaria. Patent US2023017373 describe the use of mito-atovaquone for the treatment of several types of cancer. Mito-Atovaquone demonstrated antiproliferative activity in cell lines of pancreatic cancer, lung cancer and brain cancer and inhibited tumor growth in syngeneic mouse models and in animals genetically prone to breast cancer. Mito-Atovaquone has the potential to be used successfully in the treatment of various types of tumors.

Automated summary

Research shows that mito-Atovaquone can be used to treat various types of cancer, including pancreatic cancer, lung cancer, and brain cancer. The repurposing of this approved drug strategy saves time and investment.