Journal
CHEMICAL PHYSICS LETTERS
Volume 623, Issue -, Pages 46-50Publisher
ELSEVIER
DOI: 10.1016/j.cplett.2015.01.049
Keywords
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Funding
- European Social Fund under the Global Grant measure [VP1-3.1-SMM-07-K-03-044]
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Raman and surface enhanced Raman spectroscopies have been used to investigate interaction of L-alanyl-L-tryptophan (Ala-Trp) dipeptide with nanostructured silver surface. A highly sensitive surface enhanced Raman scattering (SERS)-based biosensor has been employed for label-free dipeptide detection and its orientation on the nanostructured surface. The synthesis of SERS substrate was based on direct silver ions reduction on hydrofluoric acid etched silicon wafer. Raman and SERS spectra of Ala-Trp were recorded in liquid to keep native environment for dipeptide. To the best of our knowledge, this work is a first attempt to analyze the structure of Ala-Trp dipeptide by Raman spectroscopy. (C) 2015 Elsevier B.V. All rights reserved.
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