Hepatitis C screening and linkage to care with a mobile clinic in Southern Denmark

Article Gastroenterology & Hepatology

Differences in the hepatitis C virus cascade of care and time to initiation of therapy among vulnerable subpopulations using a mobile unit as point-of-care

Jorge Valencia et al.

Summary: The analysis of the HCV cascade of care using a mobile point-of-care strategy in vulnerable subpopulations in Madrid found that despite the majority achieving sustained virological response, people who inject drugs require better linkage to care and treatment initiation, while individuals with alcohol use disorder and people who inject drugs need more support to complete treatment.

LIVER INTERNATIONAL (2022)

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Article Infectious Diseases

A multi-level intervention to eliminate hepatitis C from the Region of Southern Denmark: the C-Free-South project

Sandra Drose et al.

Summary: Denmark has signed the WHO strategy to eliminate hepatitis C virus (HCV) and in the absence of a national strategy for elimination, a local action plan was developed in the Region of Southern Denmark (RSD) with the aim to diagnose 90% of HCV-infected persons and treat 80% of those diagnosed by 2025. The strategy was developed by reviewing Danish data on HCV epidemiology and drug use to identify key populations for screening, linkage to care, and treatment.

BMC INFECTIOUS DISEASES (2022)

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Article Gastroenterology & Hepatology

Peer support in small towns: A decentralized mobile Hepatitis C virus clinic for people who inject drugs

Havard Midgard et al.

Summary: This study evaluated a HCV treatment model using point-of-care testing and liver disease assessment in a peer-driven mobile clinic. Results showed that this model achieved good HCV treatment uptake among people who inject drugs.

LIVER INTERNATIONAL (2022)

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Review Gastroenterology & Hepatology

Interventions to enhance testing, linkage to care, and treatment initiation for hepatitis C virus infection: a systematic review and meta-analysis

Evan B. Cunningham et al.

Summary: Despite the goal set by WHO to eliminate hepatitis C virus (HCV) as a public health threat, the uptake of HCV testing and treatment remains low. Several interventions have been found to effectively improve HCV antibody testing, HCV RNA testing, linkage to HCV care, and treatment initiation.

LANCET GASTROENTEROLOGY & HEPATOLOGY (2022)

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Review Substance Abuse

Interventions to increase linkage to care and adherence to treatment for hepatitis C among people who inject drugs: A systematic review and practical considerations from an expert panel consultation

Tanja Schwarz et al.

Summary: This systematic review aimed to evaluate the effectiveness of interventions on HCV linkage to care and adherence to treatment among people who inject drugs. The results suggest that integrated, people-centered approaches may improve engagement throughout the continuum of HCV care among people who inject drugs. However, the quality of evidence was predominantly low to moderate.

INTERNATIONAL JOURNAL OF DRUG POLICY (2022)

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Article Infectious Diseases

Emergency department testing is feasible but ineffective to eliminate hepatitis C in Denmark

Jessica Jennifer Wentworth et al.

Summary: In Denmark, a risk-based, point-of-care screening strategy in an emergency department revealed that injecting drug use was the highest risk factor for HCV-Ab positivity. Despite its feasibility, this screening strategy was ineffective, highlighting the need for further testing strategies to identify remaining hepatitis C patients.

INFECTIOUS DISEASES (2021)

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Article Gastroenterology & Hepatology