Journal
NATURE REVIEWS UROLOGY
Volume 13, Issue 10, Pages 613-626Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrurol.2016.168
Keywords
-
Categories
Ask authors/readers for more resources
Benign prostatic hyperplasia (BPH) is the most common urological disease in elderly men. Epidemiological data suggest a causal link between this condition and prostatic inflammation. The prostate is an immune-competent organ characterized by the presence of a complex immune system. Several stimuli, including infectious agents, urinary reflux, metabolic syndrome, the ageing process, and autoimmune response, have been described as triggers for the dysregulation of the prostatic immune system via different molecular pathways involving the development of inflammatory infiltrates. From a pathophysiological standpoint, subsequent tissue damage and chronic tissue heating could result in the development of BPH nodules.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available