4.5 Article

Relationship between Composite Dietary Antioxidant Index and Aging

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

Muscle distribution in relation to all-cause and cause-specific mortality in young and middle-aged adults

Chen-An Liu et al.

Summary: According to the COX regression analysis, the distribution of muscle mass across different body parts, such as upper limbs, lower limbs, trunk, gynoid, and total lean mass, is positively associated with the survival rate of participants. Changes in the lean mass ratio and android-gynoid ratio attenuate the protective effect of lean mass. Age and sex act as potential modifiers, and the relationship between lean mass and prognosis is more significant in men and middle-aged participants. The impact of lean mass on prognosis is more substantial in the near-term rather than the long-term.

JOURNAL OF TRANSLATIONAL MEDICINE (2023)

Review Biochemistry & Molecular Biology

Hallmarks of aging: An expanding universe

Carlos Lopez-Otin et al.

Summary: Aging is driven by hallmarks that manifest with age, accelerate aging when accentuated experimentally, and can be decelerated, stopped, or reversed with therapeutic interventions. The twelve proposed hallmarks of aging include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis. These hallmarks are interconnected with each other and with the recently proposed hallmarks of health.
Article Oncology

Composite dietary antioxidant index and the risk of colorectal cancer: Findings from the Singapore Chinese Health Study

Yi-Chuan Yu et al.

Summary: This study, based on the Singapore Chinese Health Study, found a negative association between food-based antioxidants and the risk of colorectal cancer (CRC). Individuals with higher composite dietary antioxidant index (CDAI) had a lower risk of developing CRC.

INTERNATIONAL JOURNAL OF CANCER (2022)

Review Cell Biology

Oxidative Stress in Human Pathology and Aging: Molecular Mechanisms and Perspectives

Younis Ahmad Hajam et al.

Summary: This article discusses the mechanism of oxidative stress and its relationship with aging and related diseases.

CELLS (2022)

Article Medicine, General & Internal

Biological aging mediates the associations between urinary metals and osteoarthritis among US adults

Li Chen et al.

Summary: This study evaluated the associations between urinary metals and osteoarthritis (OA) risk, and found that biological aging partly mediated these associations.

BMC MEDICINE (2022)

Article Oncology

Novel Diagnostic and Prognostic Tools for Lung Cancer Cachexia: Based on Nutritional and Inflammatory Status

Chen-An Liu et al.

Summary: Cachexia is a common complication in lung cancer patients and significantly affects their quality of life and survival time. This study analyzed the predictors and prognostic factors of lung cancer cachexia and developed a convenient and accurate clinical prediction tool for oncologists.

FRONTIERS IN ONCOLOGY (2022)

Review Biochemistry & Molecular Biology

Selenium: An Antioxidant with a Critical Role in Anti-Aging

Geir Bjorklund et al.

Summary: Selenium plays an important role in improving antioxidant defense, immune functions, and metabolic homeostasis. Inadequate selenium status can accelerate the aging process and increase the risk of diseases. This review introduces the role of selenium in aging mechanisms and its potential clinical implications.

MOLECULES (2022)

Article Cardiac & Cardiovascular Systems

Association of the Composite dietary antioxidant index with all-cause and cardiovascular mortality: A prospective cohort study

Lei Wang et al.

Summary: According to the study, a high intake of dietary antioxidants is associated with a reduced risk of all-cause and cardiovascular mortality. Consuming an antioxidant-rich diet can significantly prevent deaths related to cardiovascular diseases.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

Review Biochemistry & Molecular Biology

Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies

Krasimira Aleksandrova et al.

Summary: This review of observational studies and intervention trials in the past five years found that plant-based dietary patterns, such as the Mediterranean and DASH diet, were associated with lower levels of oxidative stress and inflammation. On the other hand, western and fast food diets were positively associated with higher levels of oxidative stress and inflammation. Further large-scale intervention trials are needed to confirm these findings.

REDOX BIOLOGY (2021)

Review Cell Biology

Mitochondria: Their relevance during oocyte ageing

Jiska van der Reest et al.

Summary: The oocyte is characterized by a high number of mitochondria with unique architecture, essential for energy production and cellular functions. Mitochondrial dysfunction, caused by aging or stress, can impact oocyte maturation and contribute to reproductive aging and age-related diseases. Targeting mitochondria could potentially promote oocyte rejuvenation and reproductive health.

AGEING RESEARCH REVIEWS (2021)

Review Endocrinology & Metabolism

Protective Mechanism of Humanin Against Oxidative Stress in Aging-Related Cardiovascular Diseases

He Cai et al.

Summary: Physiological reactive oxygen species (ROS) play important roles in intercellular signal transduction, while oxidative and antioxidation systems maintain a dynamic equilibrium. Increased ROS levels may lead to oxidative stress damage and contribute to the pathogenesis of aging-related cardiovascular diseases. Humanin exerts protective effects on atherosclerosis, ischemia-reperfusion injury, and heart failure by modulating multiple redox signaling pathways.

FRONTIERS IN ENDOCRINOLOGY (2021)

Review Endocrinology & Metabolism

A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug That Enhances Healthspan and Extends Lifespan

Ibrahim Mohammed et al.

Summary: Metformin, commonly used to treat type 2 diabetes, may have anti-aging potential and improve healthspan by reducing early mortality associated with various diseases. However, the evidence regarding whether metformin can extend lifespan remains controversial.

FRONTIERS IN ENDOCRINOLOGY (2021)

Article Biochemistry & Molecular Biology

Signaling pathways and effectors of aging

Siamak Tabibzadeh

Summary: Aging is associated with aberrant function in multiple signaling pathways, including AMPK, sirtuins, FOX proteins, and Klotho. Loss of factors like Klotho can lead to premature aging, while other factors such as hydrogen sulfide and p53 play crucial roles in protecting cells against damage during aging.

FRONTIERS IN BIOSCIENCE-LANDMARK (2021)

Review Cell Biology

Ageing, age-related diseases and oxidative stress: What to do next?

Jiao Luo et al.

AGEING RESEARCH REVIEWS (2020)

Article Medicine, Research & Experimental

Melatonin inhibits cytosolic mitochondrial DNA-induced neuroinflammatory signaling in accelerated aging and neurodegeneration

Abhishek Jauhari et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Review Cell & Tissue Engineering

Therapeutic applications of adipose cell-free derivatives: a review

Yuan Cai et al.

STEM CELL RESEARCH & THERAPY (2020)

Review Nutrition & Dietetics

Vitamin C and the Lens: New Insights into Delaying the Onset of Cataract

Julie C. Lim et al.

NUTRIENTS (2020)

Review Geriatrics & Gerontology

Selenium, aging and aging-related diseases

Zhonglin Cai et al.

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2019)

Article Cell Biology

An epigenetic biomarker of aging for lifespan and healthspan

Morgan E. Levine et al.

AGING-US (2018)

Review Multidisciplinary Sciences

Facing up to the global challenges of ageing

Linda Partridge et al.

NATURE (2018)

Article Cell Biology

Biomarker signatures of aging

Paola Sebastiani et al.

AGING CELL (2017)

Article Medicine, Research & Experimental

Anti-oxidative effects of curcumin on immobilization-induced oxidative stress in rat brain, liver and kidney

Saeed Samarghandian et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Article Biochemistry & Molecular Biology

Cytochrome P450-2E1 promotes aging-related hepatic steatosis, apoptosis and fibrosis through increased nitroxidative stress

Mohamed A. Abdelmegeed et al.

FREE RADICAL BIOLOGY AND MEDICINE (2016)

Article Biochemistry & Molecular Biology

Oxidative stress response and Nrf2 signaling in aging

Hongqiao Zhang et al.

FREE RADICAL BIOLOGY AND MEDICINE (2015)

Article Medicine, General & Internal

The burden of disease in older people and implications for health policy and practice

Martin J. Prince et al.

LANCET (2015)

Review Geriatrics & Gerontology

Cigarette smoke - an aging accelerator?

David Bernhard et al.

EXPERIMENTAL GERONTOLOGY (2007)

Article Public, Environmental & Occupational Health

Development of a comprehensive dietary antioxidant index and application to lung cancer risk in a cohort of male smokers

ME Wright et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2004)