Improving the Therapeutic Relationship When Prescribing Antidepressants: A Pilot Study

Studies indicate that the quality of the doctor-patient relationship moderates the effect of pharmacotherapy. To enhance the quality of the therapeutic relationship in the pharmacotherapy of depression, we developed a brief manual with interactive materials for residents in psychiatry and their patients. In a pilot study at a psychiatric university hospital's outpatient department, we compared patient-centered treatment parameters of a first patient group treated as usual and a second patient group treated using the manual. The study had no influence on the choice of medication. In the manual group, patient satisfaction with the doctor-patient relationship increased significantly at the three-month follow-up. Depression parameters declined in both groups, without group differences. Continuation of antidepressant medication at six months was higher in the manual group. In conclusion, a simple intervention using written materials for doctors prescribing antidepressants improved doctors' and patients' satisfaction with treatment.

Automated summary

Studies show that the quality of the doctor-patient relationship plays a significant role in the effectiveness of pharmacotherapy. To improve the therapeutic relationship in the pharmacotherapy of depression, researchers developed a concise manual and interactive materials for psychiatry residents and their patients. In a pilot study, patients treated using the manual showed a significant increase in satisfaction with the doctor-patient relationship at the three-month follow-up. Both groups showed a decrease in depression symptoms, with no significant differences between them. However, the manual group had a higher rate of continuation of antidepressant medication at six months.