4.5 Article

Complications of Intrathecal Baclofen Pump Therapy: An Institutional Experience from Saudi Arabia

Journal

HEALTHCARE
Volume 11, Issue 21, Pages -

Publisher

MDPI
DOI: 10.3390/healthcare11212820

Keywords

intrathecal baclofen; spasticity; complications; outcomes; Saudi Arabia

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This retrospective cohort study analyzes the complications of intrathecal baclofen pump (ITB) treatment. The results indicate that catheter-related complications are the most common, and there is a significant relationship between catheter occlusion and the pattern of spastic quadriparesis.
The intrathecal baclofen pump (ITB) is one of the advanced treatment options in the management of spasticity. This retrospective cohort study was conducted to identify the complications of ITB treatment at a tertiary care rehabilitation facility. Various demographic and technical factors were analyzed, which are less often reported in the literature. All patients with ITB who had their refill at the ITB clinic between November 2019 and March 2020 were included. Of 48 patients, 17 patients had 18 (37.5%) ITB-related complications. Catheter-related complications were most common, whereas loss of efficacy (16.7%) and baclofen withdrawal (14.5%) were the most common outcomes of complications. Only catheter occlusion had a significant relationship with the pattern of spastic quadriparesis (p = 0.001). Gender, rehabilitation diagnosis, patients' residence, and facility of ITB placement did not have significant association. Similarly, age, distance from hospital, disease onset, ITB therapy duration, and baclofen dose were not statistically significant in relation to ITB-related complications.

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