Journal
NATURE REVIEWS NEUROSCIENCE
Volume 17, Issue 7, Pages 424-437Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn.2016.46
Keywords
-
Categories
Funding
- G. Harold and Leila Y. Mathers Charitable Foundation
- JPB Foundation
- Ipsen Pharma
- Leona M. and Harry B. Helmsley Charitable Trust grant [2012-PG-MED002]
- Paul G. Allen Foundation
- Janssen
- American Federation for Aging Research
Ask authors/readers for more resources
The scarcity of live human brain cells for experimental access has for a long time limited our ability to study complex human neurological disorders and elucidate basic neuroscientific mechanisms. A decade ago, the development of methods to reprogramme somatic human cells into induced pluripotent stem cells enabled the in vitro generation of a wide range of neural cells from virtually any human individual. The growth of methods to generate more robust and defined neural cell types through reprogramming and direct conversion into induced neurons has led to the establishment of various human reprogramming-based neural disease models.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available