Four Cases of Port-Wine Birthmark Treated with Hematoporphyrin Monomethyl Ether-Mediated Photodynamic Therapy After Radioactive Nuclide Patch Therapy

Review Medicine, General & Internal

Efficacy of photodynamic therapy in the treatment of port wine stains: A systematic review and meta-analysis

Ling Wang et al.

Summary: The present study conducted a systematic review and meta-analysis to evaluate the safety and effectiveness of photodynamic therapy (PDT) for port wine stains (PWS). The findings suggest that PDT is a safe and effective treatment for PWS, but more high-quality comparative studies are needed to strengthen this conclusion.

FRONTIERS IN MEDICINE (2023)

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Article Dermatology

The Efficacy of Hematoporphyrin Monomethyl Ether Photodynamic Therapy in Adult Patients with Port-Wine Stains: A Retrospective Study

Xin-yu Zhang et al.

Summary: This study evaluated the clinical efficacy and treatment response of HMME-PDT in adult Chinese patients with port-wine stains (PWSs). The results showed that HMME-PDT is an effective and safe treatment for purple PWSs, and multiple treatments can improve the cure rate.

DERMATOLOGY AND THERAPY (2022)

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Article Dermatology

The Relationship Between the Effectiveness of HMME-PDT and the Dermoscopic Features of Port-wine Stains in Chinese Pediatric Patients: A Retrospective Study

Xin-yu Zhang et al.

Summary: This study examines the clinical efficacy and therapeutic response of HMME-PDT in pediatric Chinese patients with port-wine stains (PWS) and analyzes the association between treatment efficacy and dermoscopic features of PWS.

DERMATOLOGY AND THERAPY (2022)

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Review Biochemistry & Molecular Biology

Pathogenesis of Port-Wine Stains: Directions for Future Therapies

Lian Liu et al.

Summary: Port-wine stains (PWSs) are congenital vascular malformations involving skin and mucosa. The mechanisms behind their development and progression are still unclear. Possible causes include genetic mutations, decreased nerve elements, and cellular expression defects. While pulsed-dye laser (PDL) remains the gold standard treatment, recurrence rates are high. Topical drugs and photothermal therapy show promise in reducing recurrence and improving treatment outcomes.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Article Biochemical Research Methods