The role of red ginseng in men's reproductive health: a literature review

BackgroundRed ginseng (RG) is a traditional herb commonly used in China, Korea, and other East Asian countries. Recently, it has demonstrated a better clinical value in men's reproductive health (MRH). The present review aimed to examine the effects of RG treatment on MRH.ResultsOverall, 42 articles related to RG application in MRH were reviewed, of which 31 were animal experiments and 11 were clinical studies. Furthermore, this review analyzed the use of RG in some male reproductive diseases in clinical trials and determined the associated mechanisms of action. The mechanism of action of RG in MRH may be related to oxidative stress, regulation of sex hormones and spermatogenesis-related proteins, and anti-inflammation.ConclusionsThe application of RG for the treatment of male infertility, erectile dysfunction, and prostate diseases has the potential to contribute to MRH. ContexteLe ginseng rouge est une herbe traditionnelle couramment utilisee en Chine, en Coree et dans d'autres pays d'Asie de l'Est. Recemment, il a demontre une valeur clinique en sante reproductive des hommes. La presente revue visait a examiner les effets du traitement par ginseng rouge en sante reproductive masculine.ResultatsAu total, 42 articles lies a l'utilisation du traitement par ginseng rouge en situation d'alterations de la sante reproductive male ont ete examines, dont 31 etaient des experiences sur des animaux et 11 des etudes cliniques. De plus, cette revue a analyse l'utilisation du ginseng rouge dans certaines maladies de la reproduction masculine lors d'essais cliniques, et a determine les mecanismes d'action associes. Le mecanisme d'action du ginseng rouge en sante reproductive male peut etre lie au stress oxydatif, a la regulation des hormones sexuelles et des proteines liees a la spermatogenese, et a une action anti-inflammatoire.ConclusionsL'application du ginseng rouge pour le traitement de l'infertilite masculine, de la dysfonction erectile et des maladies de la prostate a le potentiel de contribuer a la sante reproductive des hommes.

Automated summary

Red ginseng (RG), a traditional herb commonly used in China, Korea, and other East Asian countries, has demonstrated a better clinical value in men's reproductive health (MRH). This review examines the effects of RG treatment on MRH, including its potential application in male infertility, erectile dysfunction, and prostate diseases. The mechanisms of action of RG in MRH may involve oxidative stress, regulation of sex hormones and spermatogenesis-related proteins, and anti-inflammation.