Related references
Note: Only part of the references are listed.Insulator dysfunction and oncogene activation in IDH mutant gliomas
William A. Flavahan et al.
NATURE (2016)
Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
Xiaoyang Zhang et al.
NATURE GENETICS (2016)
CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation
Matthias Merkenschlager et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 17 (2016)
The 3D Genome as Moderator of Chromosomal Communication
Job Dekker et al.
CELL (2016)
3D Chromosome Regulatory Landscape of Human Pluripotent Cells
Xiong Ji et al.
CELL STEM CELL (2016)
Local Genome Topology Can Exhibit an Incompletely Rewired 3D-Folding State during Somatic Cell Reprogramming
Jonathan A. Beagan et al.
CELL STEM CELL (2016)
Cell-of-Origin-Specific 3D Genome Structure Acquired during Somatic Cell Reprogramming
Peter Hugo Lodewijk Krijger et al.
CELL STEM CELL (2016)
The three-dimensional cancer genome
M. Ryan Corces et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2016)
Gene regulation and chromatin organization: relevance of cohesin mutations to human disease
Erwan Watrin et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2016)
Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity
Iain Williamson et al.
DEVELOPMENT (2016)
The second decade of 3C technologies: detailed insights into nuclear organization
Annette Denker et al.
GENES & DEVELOPMENT (2016)
Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments
Patrick J. Wijchers et al.
MOLECULAR CELL (2016)
Hierarchy within the mammary STAT5-driven Wap super-enhancer
Ha Youn Shin et al.
NATURE GENETICS (2016)
Genetic dissection of the α-globin super-enhancer in vivo
Deborah Hay et al.
NATURE GENETICS (2016)
Activation of proto-oncogenes by disruption of chromosome neighborhoods
Denes Hnisz et al.
SCIENCE (2016)
Breaking TADs: How Alterations of Chromatin Domains Result in Disease
Dario G. Lupianez et al.
TRENDS IN GENETICS (2016)
Formation of Chromosomal Domains by Loop Extrusion
Geoffrey Fudenberg et al.
CELL REPORTS (2016)
Complete haplotype phasing of the MHC and KIR loci with targeted HaploSeq
Siddarth Selvaraj et al.
BMC GENOMICS (2015)
A Long-Distance Chromatin Affair
Annette Denker et al.
CELL (2015)
Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions
Fabian Grubert et al.
CELL (2015)
Population Variation and Genetic Control of Modular Chromatin Architecture in Humans
Sebastian M. Waszak et al.
CELL (2015)
Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions
Dario G. Lupianez et al.
CELL (2015)
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function
Ya Guo et al.
CELL (2015)
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis
Aaron D. Viny et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms
Jasper Mullenders et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
CTCF Binding Polarity Determines Chromatin Looping
Elzo de Wit et al.
MOLECULAR CELL (2015)
Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers
Denes Hnisz et al.
MOLECULAR CELL (2015)
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism
Derek A. Oldridge et al.
NATURE (2015)
Chromatin architecture reorganization during stem cell differentiation
Jesse R. Dixon et al.
NATURE (2015)
Integrative analysis of 111 reference human epigenomes
Anshul Kundaje et al.
NATURE (2015)
A global reference for human genetic variation
David M. Altshuler et al.
NATURE (2015)
Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo
Matthew T. Maurano et al.
NATURE GENETICS (2015)
CTCF/cohesin-binding sites are frequently mutated in cancer
Riku Katainen et al.
NATURE GENETICS (2015)
Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
Borbala Mifsud et al.
NATURE GENETICS (2015)
The selection and function of cell type-specific enhancers
Sven Heinz et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
The Mediator complex: a central integrator of transcription
Benjamin L. Allen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
Melina Claussnitzer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders
Carlos Gomez-Marin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
Adrian L. Sanborn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation
Varun Narendra et al.
SCIENCE (2015)
Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome
Yu Gyoung Tak et al.
EPIGENETICS & CHROMATIN (2015)
Comparative Hi-C Reveals that CTCF Underlies Evolution of Chromosomal Domain Architecture
Matteo Vietri Rudan et al.
CELL REPORTS (2015)
Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation
Muhammad A. Zabidi et al.
NATURE (2015)
Getting the genome in shape: the formation of loops, domains and compartments
Britta A. M. Bouwman et al.
GENOME BIOLOGY (2015)
Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution
Pelin Sahlen et al.
GENOME BIOLOGY (2015)
Reactivation of Developmentally Silenced Globin Genes by Forced Chromatin Looping
Wulan Deng et al.
CELL (2014)
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Suhas S. P. Rao et al.
CELL (2014)
A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia
Stefan Groeschel et al.
CELL (2014)
Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes
Jill M. Dowen et al.
CELL (2014)
Functional and topological characteristics of mammalian regulatory domains
Orsolya Symmons et al.
GENOME RESEARCH (2014)
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Paul A. Northcott et al.
NATURE (2014)
Topologically associating domains are stable units of replication-timing regulation
Benjamin D. Pope et al.
NATURE (2014)
Obesity-associated variants within FTO form long-range functional connections with IRX3
Scott Smemo et al.
NATURE (2014)
Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping
Paula J. P. de Vree et al.
NATURE BIOTECHNOLOGY (2014)
Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment
Jim R. Hughes et al.
NATURE GENETICS (2014)
Long-range enhancers regulating Myc expression are required for normal facial morphogenesis
Veil Vural Uslu et al.
NATURE GENETICS (2014)
CTCF: an architectural protein bridging genome topology and function
Chin-Tong Ong et al.
NATURE REVIEWS GENETICS (2014)
Transcriptional enhancers: from properties to genome-wide predictions
Daria Shlyueva et al.
NATURE REVIEWS GENETICS (2014)
Quantitative analysis of genomic element interactions by molecular colony technique
Alexey A. Gavrilov et al.
NUCLEIC ACIDS RESEARCH (2014)
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
Danielle Welter et al.
NUCLEIC ACIDS RESEARCH (2014)
Defining functional DNA elements in the human genome
Manolis Kellis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
Marc R. Mansour et al.
SCIENCE (2014)
Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells
Pierre Therizols et al.
SCIENCE (2014)
CTCF Haploinsufficiency Destabilizes DNA Methylation and Predisposes to Cancer
Christopher J. Kemp et al.
CELL REPORTS (2014)
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
Warren A. Whyte et al.
CELL (2013)
Super-Enhancers in the Control of Cell Identity and Disease
Denes Hnisz et al.
CELL (2013)
Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation
Kyong-Rim Kieffer-Kwon et al.
CELL (2013)
Genome Architecture: Domain Organization of Interphase Chromosomes
Wendy A. Bickmore et al.
CELL (2013)
Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
Jennifer E. Phillips-Cremins et al.
CELL (2013)
Long-Range Chromatin Contacts in Embryonic Stem Cells Reveal a Role for Pluripotency Factors and Polycomb Proteins in Genome Organization
Matthew Denholtz et al.
CELL STEM CELL (2013)
Identical cells with different 3D genomes; cause and consequences?
Peter H. L. Krijger et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2013)
An integrated Holo-Enhancer Unit Defines Tissue and Gene Specificity of the Fgf8 Regulatory Landscape
Mirna Marinic et al.
DEVELOPMENTAL CELL (2013)
The Hierarchy of the 3D Genome
Johan H. Gibcus et al.
MOLECULAR CELL (2013)
Topology of mammalian developmental enhancers and their regulatory landscapes
Wouter de Laat et al.
NATURE (2013)
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure
Takashi Nagano et al.
NATURE (2013)
The pluripotent genome in three dimensions is shaped around pluripotency factors
Elzo de Wit et al.
NATURE (2013)
Mutational landscape and significance across 12 major cancer types
Cyriac Kandoth et al.
NATURE (2013)
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms
Ayana Kon et al.
NATURE GENETICS (2013)
Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data
Job Dekker et al.
NATURE REVIEWS GENETICS (2013)
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
Timothy J. Ley et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
GWAS3D: detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications
Mulin Jun Li et al.
NUCLEIC ACIDS RESEARCH (2013)
A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs
Guillaume Andrey et al.
SCIENCE (2013)
Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq
Cosmas D. Arnold et al.
SCIENCE (2013)
Complex genomic rearrangement in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula
Maki Fukami et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2012)
Controlling Long-Range Genomic Interactions at a Native Locus by Targeted Tethering of a Looping Factor
Wulan Deng et al.
CELL (2012)
Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation
Guoliang Li et al.
CELL (2012)
Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly
Laura A. Lettice et al.
DEVELOPMENTAL CELL (2012)
HERC2 rs12913832 modulates human pigmentation by attenuating chromatin-loop formation between a long-range enhancer and the OCA2 promoter
Mijke Visser et al.
GENOME RESEARCH (2012)
Linking disease associations with regulatory information in the human genome
Marc A. Schaub et al.
GENOME RESEARCH (2012)
Widespread plasticity in CTCF occupancy linked to DNA methylation
Hao Wang et al.
GENOME RESEARCH (2012)
A map of the cis-regulatory sequences in the mouse genome
Yin Shen et al.
NATURE (2012)
The accessible chromatin landscape of the human genome
Robert E. Thurman et al.
NATURE (2012)
An integrated map of genetic variation from 1,092 human genomes
David M. Altshuler et al.
NATURE (2012)
Topological domains in mammalian genomes identified by analysis of chromatin interactions
Jesse R. Dixon et al.
NATURE (2012)
Spatial partitioning of the regulatory landscape of the X-inactivation centre
Elphege P. Nora et al.
NATURE (2012)
Robust 4C-seq data analysis to screen for regulatory DNA interactions
Harmen J. G. van de Werken et al.
NATURE METHODS (2012)
Transcription factors: from enhancer binding to developmental control
Francois Spitz et al.
NATURE REVIEWS GENETICS (2012)
Self-organization of domain structures by DNA-loop-extruding enzymes
Elnaz Alipour et al.
NUCLEIC ACIDS RESEARCH (2012)
Comprehensive Identification and Annotation of Cell Type-Specific and Ubiquitous CTCF-Binding Sites in the Human Genome
Hebing Chen et al.
PLOS ONE (2012)
Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus
Thomas Montavon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
Matthew T. Maurano et al.
SCIENCE (2012)
Regulation of the Probability of Mouse Odorant Receptor Gene Choice
Mona Khan et al.
CELL (2011)
Polycomb-Dependent Regulatory Contacts between Distant Hox Loci in Drosophila
Frederic Bantignies et al.
CELL (2011)
A Regulatory Archipelago Controls Hox Genes Transcription in Digits
Thomas Montavon et al.
CELL (2011)
The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA
Erik Splinter et al.
GENES & DEVELOPMENT (2011)
A unique chromatin signature uncovers early developmental enhancers in humans
Alvaro Rada-Iglesias et al.
NATURE (2011)
Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor
Sandra Ruf et al.
NATURE GENETICS (2011)
CTCF-mediated functional chromatin interactome in pluripotent cells
Lusy Handoko et al.
NATURE GENETICS (2011)
Genome-nuclear lamina interactions and gene regulation
Jop Kind et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
A Specific Mutation in the Distant Sonic Hedgehog (SHH) Cis-Regulator (ZRS) Causes Werner Mesomelic Syndrome (WMS) While Complete ZRS Duplications Underlie Haas Type Polysyndactyly and Preaxial Polydactyly (PPD) With or Without Triphalangeal Thumb
Dagmar Wieczorek et al.
HUMAN MUTATION (2010)
Mediator and cohesin connect gene expression and chromatin architecture
Michael H. Kagey et al.
NATURE (2010)
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
Kiran Musunuru et al.
NATURE (2010)
A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings
Tomoko Sagai et al.
DEVELOPMENT (2009)
An oestrogen-receptor-α-bound human chromatin interactome
Melissa J. Fullwood et al.
NATURE (2009)
Inactivation of the Fto gene protects from obesity
Julia Fischer et al.
NATURE (2009)
Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence
Sabina Benko et al.
NATURE GENETICS (2009)
Adventitious changes in long-range gene expression caused by polymorphic structural variation and promoter competition
Karen M. Lower et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
Erez Lieberman-Aiden et al.
SCIENCE (2009)
Cohesins functionally associate with CTCF on mammalian chromosome arms
Vania Parelho et al.
CELL (2008)
CTCF regulates cell cycle progression of αβ T cells in the thymus
Helen Heath et al.
EMBO JOURNAL (2008)
Cohesin mediates transcriptional insulation by CCCTC-binding factor
Kerstin S. Wendt et al.
NATURE (2008)
Local and cis effects of the H element on expression of odorant receptor genes in mouse
Stefan H. Fuss et al.
CELL (2007)
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
Marieke Simonis et al.
NATURE GENETICS (2006)
Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements
Josee Dostie et al.
GENOME RESEARCH (2006)
CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus
Erik Splinter et al.
GENES & DEVELOPMENT (2006)
A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter
Marco De Gobbi et al.
SCIENCE (2006)
A functional screen for sonic hedgehog regulatory elements across a 1 Mb interval identifies long-range ventral forebrain enhancers
YS Jeong et al.
DEVELOPMENT (2006)
Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb
T Sagai et al.
DEVELOPMENT (2005)
CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species
TM Yusufzai et al.
MOLECULAR CELL (2004)
Megabase deletions of gene deserts result in viable mice
MA Nóbrega et al.
NATURE (2004)
The β-globin nuclear compartment in development and erythroid differentiation
RJ Palstra et al.
NATURE GENETICS (2003)
A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly
LA Lettice et al.
HUMAN MOLECULAR GENETICS (2003)
Looping and interaction between hypersensitive sites in the active β-globin locus
B Tolhuis et al.
MOLECULAR CELL (2002)
Promoter choice determines splice site selection in protocadherin α and -γ pre-mRNA splicing
B Tasic et al.
MOLECULAR CELL (2002)
Targeted deletion of 5′HS1 and 5′HS4 of the β-globin locus control region reveals additive activity of the DNaseI hypersensitive sites
MA Bender et al.
BLOOD (2001)
Initial sequencing and analysis of the human genome
ES Lander et al.
NATURE (2001)
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
AC Bell et al.
NATURE (2000)
Share Paper
