Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 17, Issue 12, Pages 741-742Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm.2016.151
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Funding
- NHGRI NIH HHS [R01 HG003143] Funding Source: Medline
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The spatial organization of genomes is studied using microscopy-and chromosome conformation capture (3C)-based methods. The two types of methods produce data that are often consistent, but there are cases where they appear discordant. These cases provide opportunities to derive better models of chromatin folding, which can reconcile the datasets.
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