Journal
LIFE-BASEL
Volume 13, Issue 10, Pages -Publisher
MDPI
DOI: 10.3390/life13101989
Keywords
assisted reproductive technology; noninvasive assessment; oocyte morphology and quality; oocyte biomechanical features; healthy offspring
Categories
Ask authors/readers for more resources
This paper provides an analytical review of the current literature on the correlation between ovarian stimulation procedures and oocyte/embryo quality. It discusses various aspects of oocyte quality, including morphological features, oocyte competence, and the surrounding environment. It also introduces the main noninvasive features and novel approaches to biomechanical parameters that may be correlated with the competence of embryos to produce a healthy pregnancy and live birth.
Invasive and noninvasive features are normally applied to select developmentally competent oocytes and embryos that can increase the take-home baby rates in assisted reproductive technology. The noninvasive approach mainly applied to determine oocyte and embryo competence has been, since the early days of IVF, the morphological evaluation of the mature cumulus-oocyte complex at the time of pickup, first polar body, zona pellucida thickness, perivitelline space and cytoplasm appearance. Morphological evaluation of oocyte quality is one of the options used to predict successful fertilization, early embryo development, uterine implantation and the capacity of an embryo to generate a healthy pregnancy to term. Thus, this paper aims to provide an analytical revision of the current literature relating to the correlation between ovarian stimulation procedures and oocyte/embryo quality. In detail, several aspects of oocyte quality such as morphological features, oocyte competence and its surrounding environment will be discussed. In addition, the main noninvasive features as well as novel approaches to biomechanical parameters of oocytes that might be correlated with the competence of embryos to produce a healthy pregnancy and live birth will be illustrated.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available