Journal
CHEMOSENSORS
Volume 11, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/chemosensors11080429
Keywords
metal-organic frameworks (MOFs); glucose detection; synthesis; electrochemical sensor; optical sensor; wearable sensor
Ask authors/readers for more resources
Metal-organic frameworks (MOFs) are widely used in various fields due to their tunable pores, functional sites, stable structure, and multi-functionality. They play a major role in glucose detection by serving as a signal transducer or functional substrate. This review introduces the general synthetic strategies of MOF-based materials and detection methods for glucose detection, as well as the novel MOF-based glucose detection devices.
Metal-organic frameworks (MOFs), constructed by coordination between metal-containing nodes and organic linkers, are widely used in various fields due to the advantages of tunable pores, diverse functional sites, stable structure, and multi-functionality. It should be noted that MOF-based materials play a major role in glucose detection, serving as a signal transducer or functional substrate for embedding nanoparticles/enzymes. Diabetes is one of the most common and fast-growing diseases worldwide, whose main clinical manifestation is high blood sugar levels. Therefore, accurate, sensitive, and point-of-care glucose detection is necessary. This review orderly introduces general synthetic strategies of MOF-based materials (pristine MOF, nanoparticles, or enzymes-modified MOF and MOF-derived materials) and detection methods (electrochemical and optical methods) for glucose detection. Then, the review refers to the novel MOF-based glucose detection devices (flexible wearable devices and microfluidic chips), which enable non-invasive continuous glucose monitoring or low-cost microscale detection. On the basis of describing the development of glucose sensors based on MOF materials in the past five years, the review presents merits, demerits, and possible improvements of various detection methods.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available