☆ 4.6 Review

Bone Disorders in Pediatric Chronic Kidney Disease: A Literature Review

BIOLOGY-BASEL (2023)

Related references

Note: Only part of the references are listed.

Article Urology & Nephrology

Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Elaine Ku et al.

Summary: Anemia is common in chronic kidney disease patients and is associated with adverse clinical outcomes. Recent research has focused on hypoxia-inducible factor-prolyl hydroxylase inhibitors (HIF-PHIs) as a potential treatment for anemia in these patients.

KIDNEY INTERNATIONAL (2023)

Add to Collection

Article Pediatrics

Diagnosis and management of mineral and bone disorders in infants with CKD: clinical practice points from the ESPN CKD-MBD and Dialysis working groups and the Pediatric Renal Nutrition Taskforce

Justine Bacchetta et al.

Summary: Infants with CKD are highly susceptible to mineral and bone disorders, and this position paper provides guidelines for diagnosing and managing CKD-MBD in infants. The paper includes 34 clinical practice points, such as dietary control of calcium and phosphate, and medication recommendations. The strength of the statements in the paper may vary and should be tailored to individual patient needs by the treating physician.

PEDIATRIC NEPHROLOGY (2023)

Add to Collection

Article Urology & Nephrology

Bone Mineral Density and Vascular Calcification in Children and Young Adults With CKD 4 to 5 or on Dialysis

Alexander D. Lalayiannis et al.

Summary: This multicenter longitudinal study found that while older adults with chronic kidney disease (CKD) may experience increases in bone mineral density (BMD), they can still develop vascular calcification. In contrast, the growing skeleton of children and young adults with CKD may offer protection against extraosseous calcification. These findings suggest that the growing skeleton may have a buffering capacity against non-skeletal calcification.

KIDNEY INTERNATIONAL REPORTS (2023)

Add to Collection

Review Biology

Malnutrition Patterns in Children with Chronic Kidney Disease

Vasiliki Karava et al.

Summary: Malnutrition is common in children with chronic kidney disease (CKD), with both undernutrition and overnutrition prevalent. Muscle wasting is the key feature of protein energy wasting (PEW), preceding fat loss and leading to fatigue and musculoskeletal decline. CKD-related wasting processes, reduced physical activity, and obesity-induced inflammatory diseases contribute to the accumulation of fat mass and deficits in muscle mass and strength. Abdominal obesity is also prevalent in children with CKD, increasing cardiometabolic risk. This review emphasizes the importance of body composition assessment, discusses the pathogenetic mechanisms, and highlights the benefits of growth hormone therapy and physical activity in managing malnutrition in pediatric CKD.

LIFE-BASEL (2023)

Add to Collection

Article Pediatrics

Cardiometabolic Risk Factors in Pediatric Kidney Transplant Recipients

Seha Kamil Saygili et al.

Summary: This study investigates the prevalence of metabolic syndrome in pediatric kidney transplant recipients and its association with cardiovascular disease and graft function. Results show that cardiometabolic risk factors are common in these patients, with approximately one-fifth diagnosed with metabolic syndrome. Left ventricular hypertrophy is much more common among patients with metabolic syndrome. However, there is no relationship between metabolic syndrome and graft dysfunction.

TURKISH ARCHIVES OF PEDIATRICS (2023)

Add to Collection

Article Pediatrics

Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce

Stella Stabouli et al.

Summary: Obesity and metabolic syndrome due to the global obesity epidemic have negative impacts on children with chronic kidney disease, increasing cardiovascular risks and exacerbating kidney function loss. The Pediatric Renal Nutrition Taskforce provides clinical practice recommendations for the nutritional management of children with CKD, focusing on non-pharmacological treatment including diet, physical activity, and behavior modification.

PEDIATRIC NEPHROLOGY (2022)

Add to Collection

Article Urology & Nephrology

Skeletal Outcomes in Children and Young Adults with Glomerular Disease

Amy J. Goodwin Davies et al.

Summary: Children and young adults with glomerular disease have a significantly higher burden of skeletal complications than the general pediatric population.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2022)

Add to Collection

Article Urology & Nephrology

Pediatric Mineral and Bone Disorder of Chronic Kidney Disease and Cardiovascular Disease

Kirsten Kusumi et al.

Summary: Chronic kidney disease is a common condition that significantly impacts patients' lifespan and quality of life, with cardiovascular disease being the leading cause of mortality. The relationships between renal, bone, and cardiovascular diseases have led to the renaming of the complex nature of these conditions as mineral and bone disorder of chronic kidney disease. Managing bone disease well can have a positive impact on cardiovascular disease. Pediatric nephrologists face additional challenges in managing mineral and bone disorder of chronic kidney disease, particularly related to linear growth and skeletal maturation.

ADVANCES IN CHRONIC KIDNEY DISEASE (2022)

Add to Collection

Review Endocrinology & Metabolism

Bone Disease in CKD in Children

Fernando Santos et al.

Summary: This manuscript focuses on mineral and bone disorders of chronic kidney disease (MBD-CKD) in pediatric patients, covering the underlying pathophysiology, causes and clinical profile of growth retardation, alterations in the growth plate, strategies for optimizing growth, and medical recommendations for prevention and treatment.

CALCIFIED TISSUE INTERNATIONAL (2021)

Add to Collection

Article Medical Laboratory Technology

Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents

Ann Vissing Landgrebe et al.

Summary: Concentrations of PTH, vitamin D, calcium, and phosphate in children and adolescents vary with age, sex, and season, which should be taken into consideration when screening for and treating imbalances in bone metabolism.

CLINICA CHIMICA ACTA (2021)

Add to Collection

Article Urology & Nephrology

Controversies in optimal anemia management: conclusions from a Kidney Disease: Improving (KDIGO) Conference

Jodie L. Babitt et al.

Summary: Chronic kidney disease is often associated with anemia and disordered iron homeostasis, which have significant adverse consequences. In 2012, KDIGO issued guidelines for managing anemia in chronic kidney disease, and in 2019, they convened conferences to review new evidence and controversies related to iron and anemia treatment. The first conference focused on iron-related issues like diagnostic challenges, treatment options and patient outcomes.

KIDNEY INTERNATIONAL (2021)

Add to Collection

Review Urology & Nephrology

Adverse Consequences of Chronic Kidney Disease on Bone Health in Children

Juhi Kumar et al.

Summary: Chronic kidney disease (CKD) mineral bone disorder has long-term effects on skeletal integrity and growth, which can lead to bone deformities, poor linear growth, and high rates of fractures in pediatric CKD patients. New imaging modalities such as high-resolution peripheral quantitative computed tomography show promise in assessing bone mineral density comprehensively and predicting incident fractures. However, the lack of large-scale studies on bone histology and correlations with serum biomarkers has resulted in the absence of evidence-based guidelines and suboptimal management of CKD mineral bone disorder in children with CKD.

SEMINARS IN NEPHROLOGY (2021)

Add to Collection

Article Transplantation

Bone evaluation in paediatric chronic kidney disease: clinical practice points from the European Society for Paediatric Nephrology CKD-MBD and Dialysis working groups and CKD-MBD working group of the ERA-EDTA

Sevcan A. Bakkaloglu et al.

Summary: Mineral and bone disorder (MBD) is common in children with chronic kidney disease (CKD), leading to challenges in clinical diagnosis and management due to the lack of high-quality evidence and wide variations in clinical practice. Assessing bone disease in children with CKD requires careful consideration of clinical practice points (CPPs) and further research in this area is recommended.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

Add to Collection

Review Pediatrics

Assessing bone mineralisation in children with chronic kidney disease: what clinical and research tools are available?

A. D. Lalayiannis et al.

PEDIATRIC NEPHROLOGY (2020)

Add to Collection

Article Pediatrics

The dietary management of calcium and phosphate in children with CKD stages 2-5 and on dialysis-clinical practice recommendation from the Pediatric Renal Nutrition Taskforce

Louise McAlister et al.

PEDIATRIC NEPHROLOGY (2020)

Add to Collection

Article Pediatrics

Cinacalcet studies in pediatric subjects with secondary hyperparathyroidism receiving dialysis

Bradley A. Warady et al.

PEDIATRIC NEPHROLOGY (2020)

Add to Collection

Review Pediatrics

Strategies for Optimizing Growth in Children With Chronic Kidney Disease

Dieter Haffner

FRONTIERS IN PEDIATRICS (2020)

Add to Collection

Review Urology & Nephrology

An Overview of Rickets in Children

Rahul Chanchlani et al.

KIDNEY INTERNATIONAL REPORTS (2020)

Add to Collection

Article Urology & Nephrology

Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease

Jens Drube et al.

NATURE REVIEWS NEPHROLOGY (2019)

Add to Collection

Article Pediatrics

Effects of obesity and metabolic syndrome on cardiovascular outcomes in pediatric kidney transplant recipients: a longitudinal study

Kristen Sgambat et al.

PEDIATRIC NEPHROLOGY (2018)

Add to Collection

Review Pediatrics

Anemia in chronic kidney disease

Meredith A. Atkinson et al.

PEDIATRIC NEPHROLOGY (2018)

Add to Collection

Review Oncology

The biology of normal bone remodelling

P. Katsimbri

EUROPEAN JOURNAL OF CANCER CARE (2017)

Add to Collection

Article Urology & Nephrology

Executive summary of the 2017 KDIGO Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) Guideline Update: what's changed and why it matters

Markus Ketteler et al.

KIDNEY INTERNATIONAL (2017)

Add to Collection

Article Transplantation

Clinical practice recommendations for treatment with active vitamin D analogues in children with chronic kidney disease Stages 2-5 and on dialysis

Rukshana Shroff et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2017)

Add to Collection

Editorial Material Urology & Nephrology

KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) Foreword

David C. Wheeler et al.

KIDNEY INTERNATIONAL SUPPLEMENTS (2017)

Add to Collection

Review Endocrinology & Metabolism

Bone modeling, remodeling, and skeletal health in children and adolescents: mineral accrual, assessment and treatment

Chiara Maggioli et al.

ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2017)

Add to Collection

Review Medical Laboratory Technology

The Canadian laboratory initiative on pediatric reference intervals: A CALIPER white paper

Khosrow Adeli et al.

CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES (2017)

Add to Collection

Article Urology & Nephrology

Fracture Burden and Risk Factors in Childhood CKD: Results from the CKiD Cohort Study

Michelle R. Denburg et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)

Add to Collection

Review Hematology

A Review of Pediatric Chronic Kidney Disease

C. D. W. Kaspar et al.

BLOOD PURIFICATION (2016)

Add to Collection

Review Urology & Nephrology

Skeletal manifestations of renal disease in childhood

Michelle R. Denburg

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2016)

Add to Collection

Article Urology & Nephrology

Direct inhibition of osteoblastic Wnt pathway by fibroblast growth factor 23 contributes to bone loss in chronic kidney disease

Natalia Carrillo-Lopez et al.

KIDNEY INTERNATIONAL (2016)

Add to Collection

Review Pediatrics

The role of bone in CKD-mediated mineral and vascular disease

Nadine M. Khouzam et al.

PEDIATRIC NEPHROLOGY (2015)

Add to Collection

Article Transplantation

Can we use circulating biomarkers to monitor bone turnover in CKD haemodialysis patients? Hypotheses and facts

Pierre Delanaye et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2014)

Add to Collection

Article Medicine, General & Internal

Evaluation and Management of Chronic Kidney Disease: Synopsis of the Kidney Disease: Improving Global Outcomes 2012 Clinical Practice Guideline

Paul E. Stevens et al.

ANNALS OF INTERNAL MEDICINE (2013)

Add to Collection

Article Medicine, Research & Experimental

Effect of oral sodium bicarbonate supplementation on progression of chronic kidney disease in patients with chronic metabolic acidosis: study protocol for a randomized controlled trial (SoBic-Study)

Martina Gaggl et al.

TRIALS (2013)

Add to Collection

Article Pediatrics

Assessment of dual-energy x-ray absorptiometry measures of bone health in pediatric chronic kidney disease

Lindsay M. Griffin et al.

PEDIATRIC NEPHROLOGY (2012)

Add to Collection

Article Pediatrics

Reference values for serum creatinine in children younger than 1 year of age

Dirk P. Boer et al.

PEDIATRIC NEPHROLOGY (2010)

Add to Collection

Article Urology & Nephrology

Hemoglobin decline in children with chronic kidney disease: Baseline results from the chronic kidney disease in children prospective cohort study

Jeffrey J. Fadrowski et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

Add to Collection

Article Endocrinology & Metabolism

Mineral metabolism and bone abnormalities in children with chronic renal failure

Cheryl P. Sanchez

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2008)

Add to Collection

Article Urology & Nephrology

Chronic kidney disease-mineral-bone disorder: A new paradigm

Sharon M. Moe et al.

ADVANCES IN CHRONIC KIDNEY DISEASE (2007)

Add to Collection

Article Urology & Nephrology

Design and methods of the chronic kidney disease in children (CKiD) prospective cohort study

Susan L. Furth et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)

Add to Collection

Article Cell Biology

Renal osteodystrophy in children: A systemic disease associated with cardiovascular manifestations

Craig B. Langman et al.

GROWTH HORMONE & IGF RESEARCH (2006)

Add to Collection

Review Urology & Nephrology

Definition, evaluation, and classification of renal osteodystrophy: A position statement from kidney disease: Improving global outcomes (KDIGO)

S. Moe et al.

KIDNEY INTERNATIONAL (2006)

Add to Collection

Article Cell Biology

Renal osteodystrophy: A pediatric perspective, 2005

CB Langman

GROWTH HORMONE & IGF RESEARCH (2005)

Add to Collection

Review Urology & Nephrology

Special aspects of renal osteodystrophy in children

IB Salusky et al.

SEMINARS IN NEPHROLOGY (2004)

Add to Collection

Article Transplantation

Spectrum of renal bone disease in end-stage renal failure patients not yet on dialysis

GB Spasovski et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2003)

Add to Collection

© Peeref 2019-2024. All rights reserved.