Journal
FRONTIERS IN CARDIOVASCULAR MEDICINE
Volume 10, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fcvm.2023.1260478
Keywords
spontaneous coronary artery dissection; acute coronary syndrome; pathophysiology; women's health; pregnancy; fibromuscular dysplasia
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This review provides contemporary knowledge of the pathophysiology of spontaneous coronary artery dissection (SCAD) and possible therapeutic solutions, discussing the prevalence, etiology, and challenges in treatment of SCAD.
Spontaneous coronary artery dissection (SCAD) accounts for 1.7%-4% of all acute coronary syndrome presentations, particularly among young women with an emerging awareness of its importance. The demarcation of acute SCAD from coronary atherothrombosis and the proper therapeutic approach still represents a major clinical challenge. Certain arteriopathies and triggers are related to SCAD, with high variability in their prevalence, and often, the cause remains unknown. The objective of this review is to provide contemporary knowledge of the pathophysiology of SCAD and possible therapeutic solutions.
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