Related references
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Summary: This study suggests that patients with mild covid-19 may experience some clinical sequelae within a year after infection, but most of them resolve within a year. Age, sex, SARS-CoV-2 variants, and vaccination status are associated with the occurrence of these sequelae.
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Carl Wahlgren et al.
Summary: This study is one of the first to report long-term recovery outcomes in patients with post-COVID-19 condition (PCC) following hospitalization. The study found that over 40% of patients still experienced persisting symptoms and limitations in daily life four months after discharge. A follow-up at 24 months showed a high prevalence of persisting symptoms and a need for long-term follow-up and rehabilitation post COVID-19 infection.
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George N. Ioannou et al.
Summary: The study aims to determine the effectiveness of COVID-19 vaccines in the healthcare system of the U.S. Department of Veterans Affairs. Research on over 2 million individuals who received the Moderna or Pfizer-BioNTech COVID19 vaccines showed a vaccine effectiveness of 69% against SARS-CoV-2 infection and 86% against SARS-CoV-2-related death.
ANNALS OF INTERNAL MEDICINE
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Qing Han et al.
Summary: Emerging evidence suggests that COVID-19 survivors may experience persistent symptoms for at least 12 months, including fatigue, dyspnea, arthromyalgia, depression, anxiety, memory loss, concentration difficulties, and insomnia. Female patients and those with more severe initial illness are more likely to suffer from long-term sequelae after one year.
Review
Peripheral Vascular Disease
Diana L. Tobler et al.
Summary: This review consolidates available data on the long-term cardiovascular complications of COVID-19 infection. Acute cardiovascular complications include myocarditis, pericarditis, acute coronary syndrome, heart failure, pulmonary hypertension, right ventricular dysfunction, and arrhythmia. Long-term follow-up shows increased incidence of arrhythmia, heart failure, acute coronary syndrome, right ventricular dysfunction, myocardial fibrosis, hypertension, and diabetes mellitus. Future research is important in understanding the clinical significance of these structural abnormalities and evaluating the effect of vaccines on preventing long-term cardiovascular complications.
CURRENT ATHEROSCLEROSIS REPORTS
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Juan P. Wisnivesky et al.
Summary: This study examined the differences in post-acute sequelae of COVID (PASC) between vaccinated and unvaccinated patients. The findings suggest that COVID vaccination is not associated with improvement in PASC.
JOURNAL OF GENERAL INTERNAL MEDICINE
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Chen Chen et al.
Summary: This study reveals a substantial prevalence of post-COVID-19 condition worldwide. Hospitalized patients have a higher prevalence compared to non-hospitalized ones. Fatigue is the most commonly reported symptom.
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Medicine, General & Internal
Pier M. Mannucci et al.
Summary: This study analyzed data from COVID-19 survivors in Lombardy to reveal the increased rates of rehospitalization, emergency room visits, and outpatient visits in the 6 months following recovery. Various medical tests and drug usage also significantly increased, indicating an increased burden on healthcare resources in the post-COVID-19 condition.
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Editorial Material
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EXERCER-LA REVUE FRANCOPHONE DE MEDECINE GENERALE
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Biochemistry & Molecular Biology
Jan Choutka et al.
Summary: Unexplained post-acute infection syndromes (PAISs) represent a group of chronic illnesses with overlapping clinical features with chronic fatigue syndrome (ME/CFS). This review summarizes the current knowledge of PAISs and discusses the need for basic biomedical research into the underlying mechanisms of these enigmatic chronic diseases, including the post-acute sequelae of SARS-CoV-2 infection (PASC).
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Biochemistry & Molecular Biology
Ziyad Al-Aly et al.
Summary: This study analyzed the US Department of Veterans Affairs national healthcare databases to investigate the occurrence of Long COVID and death risk after breakthrough SARS-CoV-2 infection. The findings showed that vaccination significantly reduced the risk of death and post-acute sequelae but did not eliminate them completely. These results underscore the importance of further research on prevention and post-acute care for breakthrough infections.
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Yan Xie et al.
Summary: This study found an increased risk and burden of incident diabetes and antihyperglycaemic use in people with COVID-19 in the post-acute phase compared to a contemporary control group. The risks and burdens of post-acute outcomes were related to the severity of the acute phase of COVID-19.
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Critical Care Medicine
Lixue Huang et al.
Summary: With the ongoing COVID-19 pandemic, a study was conducted to characterize the longitudinal evolution of health outcomes in hospitalized survivors of COVID-19 over a period of 2 years. The study found that although most survivors recovered and returned to work within 2 years, a significant proportion of them experienced persistent symptoms and health problems. These findings emphasize the need for further research and interventions to understand and reduce the risk of long-term COVID-19.
LANCET RESPIRATORY MEDICINE
(2022)
Review
Infectious Diseases
Tianqi Yang et al.
Summary: This review and meta-analysis found that previously hospitalized COVID-19 patients can experience a wide range of sequelae, with some symptoms persisting up to 1 year. Fatigue and somnipathy were the most commonly reported sequelae, while COVID-19 patients from Asia had a lower prevalence of symptoms compared to other regions.
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Medicine, General & Internal
Michela Antonelli et al.
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Infectious Diseases
Oliver J. Watson et al.
Summary: A study quantified the global impact of the first year of COVID-19 vaccination programs, finding that the vaccination has substantially altered the course of the pandemic, saving tens of millions of lives globally. However, inadequate access to vaccines in low-income countries has limited the impact, reinforcing the need for global vaccine equity and coverage.
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Ellen J. Thompson et al.
Summary: The frequency and risk factors of long COVID in community-based individuals are unclear. A study analyzing data from 10 UK population-based studies and electronic health records found wide variation in the frequency of long COVID between studies, but identified some consistent risk factors.
NATURE COMMUNICATIONS
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Roy H. Perlis et al.
Summary: This study suggests that long COVID is prevalent and associated with female gender and older age, while completion of the primary vaccination series prior to infection may reduce the risk of long COVID.
Review
Medicine, General & Internal
Daniel R. Feikin et al.
Summary: This study systematically reviewed the duration of protection provided by COVID-19 vaccines against various clinical outcomes. The findings indicate that the effectiveness or efficacy of the vaccines decreased from 1 to 6 months after full vaccination, but remained high against severe disease. Evaluating the effectiveness or efficacy of vaccines beyond 6 months is crucial for updating vaccine policies.
Article
Infectious Diseases
Oliver J. Watson et al.
Summary: The study estimated that COVID-19 vaccination has prevented millions of deaths globally between December 8, 2020, and December 8, 2021. Achieving the vaccination coverage targets set by COVAX and WHO could have prevented even more deaths. However, limited access to vaccines in low-income countries has hindered the impact, highlighting the importance of global vaccine equity.
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Respiratory System
Dominic L. Sykes et al.
Summary: Recent studies have shown that COVID-19 patients may experience lasting symptoms, with females being more likely to report residual symptoms. The phenomenon of Long-COVID may not be solely attributed to the impact of SARS-CoV-2, indicating a potential role of biopsychosocial effects of COVID-19 in its etiology.
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Mirko Di Martino et al.
Summary: This study investigated the adherence to polytherapy in patients after myocardial infarction, compared the variation attributable to hospitals of discharge and community-based providers, and identified factors influencing medication adherence. The research found that adherence is influenced by the hospital of discharge, suggesting the need for policy interventions to reduce this variability.
BMC CARDIOVASCULAR DISORDERS
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Review
Immunology
Li Yin Tan et al.
Summary: COVID-19 caused by SARS-CoV-2 can lead to severe health consequences, including acute respiratory distress syndrome and multi-organ failure, through activation of inflammatory pathways and cytokine storm. Long-term effects, particularly on the brain, are of concern.
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Daniel Ayoubkhani et al.
Summary: Patients discharged from the hospital after COVID-19 were found to have increased rates of multiorgan dysfunction, with higher risk not only limited to the elderly but also varying across ethnic groups.
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Harry Crook et al.
Summary: The long-term effects of covid-19 can affect multiple systems in the body, leading to persistent symptoms that impact patients of varying severity. These symptoms include fatigue, dyspnea, and cognitive impairment, among others. Studies discuss risk factors for acute and long covid, as well as potential therapeutic options.
BMJ-BRITISH MEDICAL JOURNAL
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Rakhee K. Ramakrishnan et al.
Summary: COVID-19 has been present for over a year with limited treatment options available. Some recovered patients experience lingering symptoms, known as long COVID-19, possibly due to a persistent immune response causing ongoing inflammation processes.
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Federica Sganga et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL
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Raghavendra Charan P. Makam et al.
AMERICAN JOURNAL OF CARDIOLOGY
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Federica Sganga et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL
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L. Pasina et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
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