4.7 Article

Reconstructing the population history of the Sinhalese, the major ethnic group in Sri($)over-bar Lanka($)over-bar

Journal

ISCIENCE
Volume 26, Issue 10, Pages -

Publisher

CELL PRESS
DOI: 10.1016/j.isci.2023.107797

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The Sinhalese population in Sri Lanka has been genetically studied, revealing their homogeneity and a trace of North Indian affiliation.
The Sinhalese are the major ethnic group in Sri lanka, inhabiting nearly the whole length and breadth of the island. They speak an Indo-European language of the Indo-Iranian branch, which is held to originate in northwestern India, going back to at least the fifth century BC. Previous genetic studies on low-resolution markers failed to infer the genomic history of the Sinhalese population. Therefore, we have performed a high-resolution fine-grained genetic study of the Sinhalese population and, in the broader context, we at-tempted to reconstruct the genetic history of Srilanka. Our allele-frequency-based analysis showed a tight cluster of Sinhalese and Tamil populations, suggesting strong gene flow beyond the boundary of ethnicity and language. Interestingly, the haplotype-based analysis preserved a trace of the North Indian affiliation to the Sinhalese population. Overall, in the South Asian context, Srilankan ethnic groups are genetically more homogeneous than others.

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