Related references
Note: Only part of the references are listed.A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer
Sandra Tietscher et al.
NATURE COMMUNICATIONS (2023)
Article MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
Yu Qian et al.
CANCER CELL (2023)
Metabolic programming and immune suppression in the tumor microenvironment
Emily N. Arner et al.
CANCER CELL (2023)
Single-cell proteomics enabled by next-generation sequencing or mass spectrometry
Hayley M. M. Bennett et al.
NATURE METHODS (2023)
Pre- and on-treatment lactate dehydrogenase as a prognostic and predictive biomarker in advanced non-small cell lung cancer
Angelina Tjokrowidjaja et al.
CANCER (2022)
NKG7 Is a T-cell-Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy
Ti Wen et al.
CANCER IMMUNOLOGY RESEARCH (2022)
Single-cell metabolomics: where are we and where are we going?
Ingela Lanekoff et al.
CURRENT OPINION IN BIOTECHNOLOGY (2022)
LDHB Overexpression Can Partially Overcome T Cell Inhibition by Lactic Acid
Sonja-Maria Decking et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
Ilaria Elia et al.
CELL METABOLISM (2022)
Macrophage diversity in cancer revisited in the era of single-cell omics
Ruo-Yu Ma et al.
TRENDS IN IMMUNOLOGY (2022)
Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencing
Xiaopei Hao et al.
REDOX BIOLOGY (2022)
Prognostic Value of Lactate Dehydrogenase in Second-Line Immunotherapy for Advanced Esophageal Squamous Cell Carcinoma
Yan Li et al.
PATHOLOGY & ONCOLOGY RESEARCH (2022)
Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer
Yuanyuan Zhang et al.
CANCER CELL (2021)
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients
Chuan Li et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization
Emad Y. Alqassim et al.
COMMUNICATIONS BIOLOGY (2021)
Single-cell metabolomics hits its stride
Caroline Seydel
NATURE METHODS (2021)
Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment
Kristen E. Pauken et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2021)
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid
McLane J. Watson et al.
NATURE (2021)
Lactate in the tumour microenvironment: From immune modulation to therapy
Zi-Hao Wang et al.
EBIOMEDICINE (2021)
Roles of tumor-associated macrophages in tumor progression: implications on therapeutic strategies
Shangli Zhu et al.
EXPERIMENTAL HEMATOLOGY & ONCOLOGY (2021)
A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer
Ayse Bassez et al.
NATURE MEDICINE (2021)
Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma
Giacomo Oliveira et al.
NATURE (2021)
Lactate dehydrogenase: a marker of diminished antitumor immunity
Sandra Van Wilpe et al.
ONCOIMMUNOLOGY (2020)
Metabolic Modulation of Immunity: A New Concept in Cancer Immunotherapy
Luana Guerra et al.
CELL REPORTS (2020)
The single-cell transcriptional landscape of mammalian organogenesis
Junyue Cao et al.
NATURE (2019)
Glycosylation in health and disease
Colin Reily et al.
NATURE REVIEWS NEPHROLOGY (2019)
Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
Yuxin Lin et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq
Dylan Kotliar et al.
ELIFE (2019)
Metabolic landscape of the tumor microenvironment at single cell resolution
Zhengtao Xiao et al.
NATURE COMMUNICATIONS (2019)
Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
Hanjie Li et al.
CELL (2019)
Long-Term Survival in Patients Responding to Anti-PD-1/PD-L1 Therapy and Disease Outcome upon Treatment Discontinuation
Marie-Lea Gauci et al.
CLINICAL CANCER RESEARCH (2019)
Single-cell RNA-seq denoising using a deep count autoencoder
Goekcen Eraslan et al.
NATURE COMMUNICATIONS (2019)
From Louvain to Leiden: guaranteeing well-connected communities
V. A. Traag et al.
SCIENTIFIC REPORTS (2019)
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer
Matthew D. Hellmann et al.
CANCER CELL (2018)
Tumor-Repopulating Cells Induce PD-1 Expression in CD8(+) T Cells by Transferring Kynurenine and AhR Activation
Yuying Liu et al.
CANCER CELL (2018)
The multifaceted role of glutathione S-transferases in cancer
Anupam Chatterjee et al.
CANCER LETTERS (2018)
Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors
Kristian M. Hargadon et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2018)
Recon3D enables a three-dimensional view of gene variation in human metabolism
Elizabeth Brunk et al.
NATURE BIOTECHNOLOGY (2018)
Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E
Peiming Zheng et al.
CELL DEATH & DISEASE (2018)
Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA
K. G. Paulson et al.
NATURE COMMUNICATIONS (2018)
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
Moshe Sade-Feldman et al.
CELL (2018)
Association Between Expression Level of PD1 by Tumor-Infiltrating CD8+ T Cells and Features of Hepatocellular Carcinoma
Hyung-Don Kim et al.
GASTROENTEROLOGY (2018)
SCANPY: large-scale single-cell gene expression data analysis
F. Alexander Wolf et al.
GENOME BIOLOGY (2018)
IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade
Mark Ayers et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance
Whijae Roh et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Resistance to checkpoint blockade therapy through inactivation of antigen presentation
Moshe Sade-Feldman et al.
NATURE COMMUNICATIONS (2017)
Metabolic Hallmarks of Tumor and immune Cells in the Tumor Microenvironment
Kathrin Renner et al.
FRONTIERS IN IMMUNOLOGY (2017)
Quantitative profiling of glycerophospholipids during mouse and human macrophage differentiation using targeted mass spectrometry
Cuiping Zhang et al.
SCIENTIFIC REPORTS (2017)
Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab
Nadeem Riaz et al.
CELL (2017)
Immune-Related Gene Expression Profiling After PD-1 Blockade in Non-Small Cell Lung Carcinoma, Head and Neck Squamous Cell Carcinoma, and Melanoma
Aleix Prat et al.
CANCER RESEARCH (2017)
Serum lactate dehydrogenase as an early marker for outcome in patients treated with anti-PD-1 therapy in metastatic melanoma
S. Diem et al.
BRITISH JOURNAL OF CANCER (2016)
LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
Almut Brand et al.
Cell Metabolism (2016)
Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
Jonathan M. Pitt et al.
IMMUNITY (2016)
Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma
Adil I. Daud et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Emerging concepts of T cell metabolism as a target of immunotherapy
Chih-Hao Chang et al.
NATURE IMMUNOLOGY (2016)
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
Joanna Ratajczak et al.
NATURE COMMUNICATIONS (2016)
Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade
Pei-Ling Chen et al.
CANCER DISCOVERY (2016)
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih-Hao Chang et al.
CELL (2015)
Genomic correlates of response to CTLA-4 blockade in metastatic melanoma
Eliezer M. Van Allen et al.
SCIENCE (2015)
Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
Naiyer A. Rizvi et al.
SCIENCE (2015)
Hypoxia-inducible factor as an angiogenic master switch
Takuya Hashimoto et al.
FRONTIERS IN PEDIATRICS (2015)
Heme oxygenase-1 and anti-inflammatory M2 macrophages
Yuji Naito et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
PD-1 blockade induces responses by inhibiting adaptive immune resistance
Paul C. Tumeh et al.
NATURE (2014)
Fatty acid remodeling in cellular glycerophospholipids following the activation of human T cells
Philippe Pierre Robichaud et al.
JOURNAL OF LIPID RESEARCH (2013)
A community-driven global reconstruction of human metabolism
Ines Thiele et al.
NATURE BIOTECHNOLOGY (2013)
Differential Regulation of Primary and Memory CD8 T Cell Immune Responses by Diacylglycerol Kinases
Jinwook Shin et al.
JOURNAL OF IMMUNOLOGY (2012)
The blockade of immune checkpoints in cancer immunotherapy
Drew M. Pardoll
NATURE REVIEWS CANCER (2012)
Apolipoprotein E Induces Antiinflammatory Phenotype in Macrophages
Daniel Baitsch et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
CD38 as a Regulator of Cellular NAD: A Novel Potential Pharmacological Target for Metabolic Conditions
Eduardo Nunes Chini
CURRENT PHARMACEUTICAL DESIGN (2009)
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
E. A. Eisenhauer et al.
EUROPEAN JOURNAL OF CANCER (2009)
Glycerol-3-phosphate acyltransferase-1 regulates murine T-lymphocyte proliferation and cytokine production
Lauren W. Collison et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation
Ken S. Lau et al.
CELL (2007)
Regulation of intracellular levels of NAD: A novel role for CD38
Pinar Aksoy et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Fuel feeds function: Energy metabolism and the T-cell response
CJ Fox et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Share Paper
