4.7 Article

Development and cadherin-mediated control of prefrontal corticostriatal projections in mice

Related references

Note: Only part of the references are listed.
Article Neurosciences

Differential Development of Dendritic Spines in Striatal Projection Neurons of Direct and Indirect Pathways in the Caudoputamen and Nucleus Accumbens

Hsiao-Ying Kuo et al.

Summary: The spatiotemporal dynamics of dendritic spine maturation of striatal spiny projection neurons (SPNs) differ between the dorsolateral striatum and dorsomedial striatum, as well as between the nucleus accumbens shell and nucleus accumbens core. In the dorsolateral striatum, spine pruning of SPNs occurs between postnatal day (P)30 and P50. In the dorsomedial striatum, the peak spine density and timing of spine pruning differ for dSPNs and iSPNs. In the nucleus accumbens shell, spine pruning occurs after P21-P30, while no significant pruning is observed for iSPNs in the lateral shell. In the nucleus accumbens core, the peak spine density is reached at different postnatal times for dSPNs and iSPNs, followed by a decline.

ENEURO (2023)

Article Biology

Coordinated cadherin functions sculpt respiratory motor circuit connectivity

Alicia N. Vagnozzi et al.

Summary: Breathing circuits depend on the coordinated activity of type I and type II cadherins to generate robust respiratory motor output. Inactivation of these cadherins during development leads to respiratory failure and reduced motor activity.

ELIFE (2022)

Article Neurosciences

Cognitive deficits and altered cholinergic innervation in young adult male mice carrying a Parkinson's disease Lrrk2G2019S knockin mutation

Ayan Hussein et al.

Summary: The Lrrk2(G2019S) mutation negatively impacts cholinergic innervation anatomically and functionally, impairing corticostriatal network function, potentially contributing to early PD-associated executive function deficits.

EXPERIMENTAL NEUROLOGY (2022)

Article Neurosciences

Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism

Jeannine A. Frei et al.

Summary: The study suggests Cadherin-11 plays a crucial role in regulating the development of neuronal circuitry, and alterations in its expression levels may contribute to the etiology of autism.

ENEURO (2021)

Article Multidisciplinary Sciences

The mouse cortico-basal ganglia-thalamic network

Nicholas N. Foster et al.

Summary: The study reveals a complex structure in the brain, with 29 functional domains transmitting information through multiple channels, influencing cognition, sensorimotor behavior, and the development of various neurological and neuropsychiatric disorders.

NATURE (2021)

Article Neurosciences

Enhancer viruses for combinatorial cell-subclass-specific labeling

Lucas T. Graybuck et al.

Summary: New genomic single-cell analysis methods have enabled rapid cell type identification, but efficient experimental access to these cell types remains a challenge. By collecting chromatin accessibility data and identifying enhancers specific to cell subclasses and types, researchers have been able to label different neuronal subclasses in the mouse cortex using recombinant adeno-associated viruses (AAVs). Through coupling enhancer viruses expressing recombinases with a newly generated transgenic mouse, strong labeling of multiple neuronal classes/subclasses can be achieved in the brain of a single transgenic animal, providing unprecedented flexibility and specificity for investigating cell types in the mouse brain and beyond.

NEURON (2021)

Review Biology

Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility

Cassandra B. Klune et al.

Summary: The medial prefrontal cortex (mPFC) along with its connections with other brain regions plays crucial roles in various behaviors such as memory, cognition, decision making, social interactions, and emotions. Dysfunction in mPFC is associated with psychiatric disorders while the delayed maturation of mPFC may lead to the emergence of complex behaviors and increased vulnerability to disruptions. Mindfulness on mPFC synaptic development and behavioral maturation is crucial to establish an integrated understanding of neural architecture and behavioral repertoires.

ELIFE (2021)

Review Neurosciences

Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS

Travis E. Faust et al.

Summary: The review discusses the impact of neural activity on developmental synaptic pruning in the mammalian central nervous system, as well as how alterations in this process can occur in neurodevelopmental disorders.

NATURE REVIEWS NEUROSCIENCE (2021)

Review Neurosciences

Dysfunction of the corticostriatal pathway in autism spectrum disorders

Wei Li et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2020)

Article Neurosciences

Prefrontal somatostatin interneurons encode fear memory

Kirstie A. Cummings et al.

NATURE NEUROSCIENCE (2020)

Article Neurosciences

LRRK2 mutation alters behavioral, synaptic, and nonsynaptic adaptations to acute social stress

Christopher A. Guevara et al.

JOURNAL OF NEUROPHYSIOLOGY (2020)

Article Neurosciences

Goal-directed actions transiently depend on dorsal hippocampus

Laura A. Bradfield et al.

NATURE NEUROSCIENCE (2020)

Article Neurosciences

Neuron-Glia Signaling in Synapse Elimination

Daniel K. Wilton et al.

Annual Review of Neuroscience (2019)

Article Multidisciplinary Sciences

Hierarchical organization of cortical and thalamic connectivity

Julie A. Harris et al.

NATURE (2019)

Article Anatomy & Morphology

Cadherin 8 regulates proliferation of cortical interneuron progenitors

Fani Memi et al.

BRAIN STRUCTURE & FUNCTION (2019)

Article Neurosciences

Optogenetic Examination of Prefrontal-Amygdala Synaptic Development

Maithe Arruda-Carvalho et al.

JOURNAL OF NEUROSCIENCE (2017)

Article Neurosciences

The mouse cortico-striatal projectome

Houri Hintiryan et al.

NATURE NEUROSCIENCE (2016)

Article Multidisciplinary Sciences

Rule learning enhances structural plasticity of long-range axons in frontal cortex

Carolyn M. Johnson et al.

NATURE COMMUNICATIONS (2016)

Review Cell Biology

Sculpting Neural Circuits by Axon and Dendrite Pruning

Martin M. Riccomagno et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 31 (2015)

Article Biochemistry & Molecular Biology

Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping

Kevin T. Beier et al.

Article Biochemistry & Molecular Biology

Type II Cadherins Guide Assembly of a Direction-Selective Retinal Circuit

Xin Duan et al.

Article Neurosciences

Anatomic and Molecular Development of Corticostriatal Projection Neurons in Mice

U. Shivraj Sohur et al.

CEREBRAL CORTEX (2014)

Article Cell Biology

Cadherin-7 Regulates Mossy Fiber Connectivity in the Cerebellum

Ken-ichiro Kuwako et al.

CELL REPORTS (2014)

Review Neurosciences

Corticostriatal connectivity and its role in disease

Gordon M. G. Shepherd

NATURE REVIEWS NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Recurrent network activity drives striatal synaptogenesis

Yevgenia Kozorovitskiy et al.

NATURE (2012)

Article Biochemical Research Methods

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin et al.

NATURE METHODS (2012)

Article Multidisciplinary Sciences

A conditional knockout resource for the genome-wide study of mouse gene function

William C. Skarnes et al.

NATURE (2011)

Article Neurosciences

Cadherin-6 Mediates Axon-Target Matching in a Non-Image-Forming Visual Circuit

Jessica A. Osterhout et al.

NEURON (2011)

Article Neurosciences

Corticostriatal and thalamostriatal synapses have distinctive properties

Jun Ding et al.

JOURNAL OF NEUROSCIENCE (2008)

Review Neurosciences

The role of the dorsal striatum in reward and decision-making

Bernard W. Balleine et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

Genome-wide atlas of gene expression in the adult mouse brain

Ed S. Lein et al.

NATURE (2007)

Article Developmental Biology

Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice

Sandra Goebbels et al.

GENESIS (2006)

Article Neurosciences

Optimal decision making and the anterior cingulate cortex

Steven W. Kennerley et al.

NATURE NEUROSCIENCE (2006)

Article Neurosciences

The role of the dorsomedial striatum in instrumental conditioning

HH Yin et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2005)

Review Behavioral Sciences

Action sets and decisions in the medial frontal cortex

MFS Rushworth et al.

TRENDS IN COGNITIVE SCIENCES (2004)

Review Neurosciences

Morphological changes in dendritic spines associated with long-term synaptic plasticity

R Yuste et al.

ANNUAL REVIEW OF NEUROSCIENCE (2001)