Serum total bilirubin and one-year prognosis of patients with coronary artery disease and psoriasis

To evaluate the potential predictive value of total bilirubin (TBIL) for one-year prognosis in patients with coronary artery disease (CAD) and psoriasis. 278 pso-riasis patients who underwent coronary angiography and were diagnosed as CAD were recruited. Baseline TBIL was measured at admission. Patients were divided into three groups according to the third tertiles of TBIL. The coronary angiog-raphy showed that lower TBIL was associated with the severity of lesion calcifica-tion. After a mean follow-up of 315 days, major adverse cardiac and cerebrovas-cular events (MACCEs) were reported in 61 patients. Compared with patients with higher TBIL tertiles, the incidence of MACCEs increased significantly in patients with middle and lower TBIL tertiles. The incidence of MACCEs in one-year follow-up was significantly different between higher and lower tertiles. The findings indicate that decreased TBIL is a potential predictor of poor prog-nosis in patients with psoriasis and CAD.

Automated summary

This study evaluates the potential predictive value of total bilirubin (TBIL) for one-year prognosis in patients with coronary artery disease (CAD) and psoriasis. The results show that lower TBIL levels are associated with the severity of coronary artery calcification, and patients with lower TBIL levels have a significantly higher incidence of major adverse cardiac and cerebrovascular events (MACCEs) in one-year follow-up.