Journal
NATURE REVIEWS CLINICAL ONCOLOGY
Volume 13, Issue 3, Pages 140-142Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrclinonc.2016.11
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Funding
- NCI NIH HHS [P30 CA008748] Funding Source: Medline
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Prostate-specific antigen (PSA)-based screening approaches are associated with reduced prostate-cancer mortality, but can lead to overdiagnosis, unnecessary biopsies and overtreatment. Two solutions for this problem exist: to abandon PSA-based screening completely, or to improve the accuracy of PSA-based screening methods to solve the benefit-to-harm equation. Herein we explore these solutions by examining three recent publications.
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