☆ 4.7 Article

Quantitative Insights and Visualization of Antimicrobial Tolerance in Mixed-Species Biofilms

BIOMEDICINES (2023)

Related references

Note: Only part of the references are listed.

Article Engineering, Environmental

H2S-releasing versatile hydrogel dressing with potent antimicrobial, anti-inflammatory, epithelialization and angiogenic capabilities for diabetic wound healing

Jiale Chen et al.

Summary: A smart hydrogel dressing capable of highly effective antimicrobial, anti-inflammatory, and promoting wound healing properties was developed using a Schiff base reaction between carboxymethyl chitosan (CMC) and polyhexamethylene guanidine (PHMG)-modified aldehyde F108 (PFC). The hydrogel released H2S and utilized the synergistic effect of DATS and PHMG to provide antimicrobial and anti-inflammatory effects. Additionally, the hydrogel promoted proliferation, migration, and vascularization of endothelial cells through the activation of p-p38 and p-ERK1/2. This study highlights the potential of the hydrogel for managing diabetic wounds.

CHEMICAL ENGINEERING JOURNAL (2023)

Add to Collection

Article Dermatology

Human skin biofilm model: translational impact on swabbing and debridement

Michael Dietrich et al.

Journal of Wound Care (2023)

Add to Collection

Article Chemistry, Applied

Chitosan and polyhexamethylene guanidine dual-functionalized cotton gauze as a versatile bandage for the management of chronic wounds

Chao Yang et al.

Summary: In this study, a versatile medical dressing with good antibacterial, hygroscopic and moisturizing abilities was developed. The dressing showed excellent immediate and long-lasting antibacterial activity and also had good biocompatibility and cell scratch healing performances.

CARBOHYDRATE POLYMERS (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Composition of Challenge Substance in Standardized Antimicrobial Efficacy Testing of Wound Antimicrobials Is Essential to Correctly Simulate Efficacy in the Human Wound Micro-Environment

Anna-Lena Severing et al.

Summary: The study found that current standard methods do not fully consider the impact of wound microenvironments on the efficacy of antimicrobial agents, and there are also differences in the antimicrobial effects against different bacteria. The composition of the challenge substance is more important than pure concentration.

BIOMEDICINES (2022)

Add to Collection

Article Microbiology

Antimicrobials cetylpyridinium-chloride and miramistin demonstrate non-inferiority and no protein-error compared to established wound care antiseptics in vitro

Julian-Dario Rembe et al.

Summary: Concerns about microbial tolerance and resistance to established antimicrobials have led to research into alternative wound treatment methods. This study compared the efficacy of different antimicrobials and investigated the effects of protein interference. The results show that CPC and MST are as effective as established wound antiseptics, even in the presence of protein.

AIMS MICROBIOLOGY (2022)

Add to Collection

Article Public, Environmental & Occupational Health

Comparative analysis of biofilm models to determine the efficacy of antimicrobials

E. K. Stuermer et al.

Summary: Biofilms are a major challenge in treating chronic wounds as antimicrobials have limited effect on them. This study compared three biofilm models using different blood sources and found that while the biofilms showed little reaction to a hypochlorous solution, they were significantly impacted by octenidine hydrochloride after 48 hours. The results suggest that both human and sheep blood based biofilm models can be effective for testing new antimicrobial substances in vitro.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2021)

Add to Collection

Review Microbiology

The Origin of Niches and Species in the Bacterial World

Fernando Baquero et al.

Summary: Niches are spaces for the biological units of selection, with every organism having its own niche. Microbial organisms constantly diversify, with the selfish behavior of new organisms limiting niche variation and ultimately facilitating speciation.

FRONTIERS IN MICROBIOLOGY (2021)

Add to Collection

Article Microbiology

In vitro Activity of Antimicrobial Wound Dressings on P. aeruginosa Wound Biofilm

Ewa Klara Stuermer et al.

Summary: The study focused on the efficacy of antimicrobial dressings for wounds with biofilms, with cadexomer-iodine (C-IOD) showing the best bacterial reduction while octendine di-hydrochloride (OCT) and ionic silver (AG) dressings did not meet expectations. Chemical interaction with biofilm extrapolymeric substance (EPS) and dressing configuration are suggested to be responsible for the diverse results, indicating a need to rethink non-debridement anti-biofilm therapy.

FRONTIERS IN MICROBIOLOGY (2021)

Add to Collection

Article Microbiology

Milieu matters: An in vitro wound milieu to recapitulate key features of, and probe new insights into, mixed-species bacterial biofilms

Snehal Kadam et al.

Summary: The study demonstrates the potential of using an in vitro wound milieu (IVWM) to mimic in vivo biofilm features, including biomass formation, metabolic activity, antibiotic tolerance, and interspecies interactions. The IVWM is simple to formulate, uses laboratory-grade components, and is compatible with standard biofilm assays, making it a promising approach for studying wound biofilms under host-relevant conditions.

BIOFILM (2021)

Add to Collection

Article Chemistry, Physical

Insights into the Polyhexamethylene Biguanide (PHMB) Mechanism of Action on Bacterial Membrane and DNA: A Molecular Dynamics Study

Shahin Sowlati-Hashjin et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2020)

Add to Collection

Article Multidisciplinary Sciences

Efficacy of antiseptics in a novel 3-dimensional human plasma biofilm model (hpBIOM)

M. Besser et al.

SCIENTIFIC REPORTS (2020)

Add to Collection

Article Microbiology

Antimicrobial Hypochlorous Wound Irrigation Solutions Demonstrate Lower Anti-biofilm Efficacy Against Bacterial Biofilm in a Complex in-vitro Human Plasma Biofilm Model (hpBIOM) Than Common Wound Antimicrobials

Julian-Dario Rembe et al.

FRONTIERS IN MICROBIOLOGY (2020)

Add to Collection

Article Biotechnology & Applied Microbiology

Transcriptional profiling of Pseudomonas aeruginosa and Staphylococcus aureus during in vitro co-culture

Mikael Tognon et al.

BMC GENOMICS (2019)

Add to Collection

Article Medicine, General & Internal

Influence of Laboratory Culture Media on in vitro Growth, Adhesion, and Biofilm Formation of Pseudomonas aeruginosa and Staphylococcus aureus

Gayan Wijesinghe et al.

MEDICAL PRINCIPLES AND PRACTICE (2019)

Add to Collection

Article Medicine, General & Internal

Understanding Real-Time Fluorescence Signals from Bacteria and Wound Tissues Observed with the MolecuLight i:X™

Monique Y. Rennie et al.

DIAGNOSTICS (2019)

Add to Collection

Article Biology

The distribution of bacterial doubling times in the wild

Beth Gibson et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2018)

Add to Collection

Article Cell Biology

Influence of human acute wound fluid on the antibacterial efficacy of different antiseptic polyurethane foam dressings: An in vitro analysis

Julian-Dario Rembe et al.

WOUND REPAIR AND REGENERATION (2018)

Add to Collection

Article Immunology

Interaction between &ITStaphylococcus aureus&IT and &ITPseudomonas aeruginosa &ITis beneficial for colonisation and pathogenicity in a mixed biofilm

Patricia M. Alves et al.

PATHOGENS AND DISEASE (2018)

Add to Collection

Article Dentistry, Oral Surgery & Medicine

Biofilms and their properties

Hakon Valen et al.

EUROPEAN JOURNAL OF ORAL SCIENCES (2018)

Add to Collection

Article Microbiology

Mechanisms of Pyocyanin Toxicity and Genetic Determinants of Resistance in Staphylococcus aureus

Michael J. Noto et al.

JOURNAL OF BACTERIOLOGY (2017)

Add to Collection

Review Multidisciplinary Sciences

Progress in and promise of bacterial quorum sensing research

Marvin Whiteley et al.

NATURE (2017)

Add to Collection

Article Dermatology

Microscopy visualisation confirms multi-species biofilms are ubiquitous in diabetic foot ulcers

Khalid Johani et al.

INTERNATIONAL WOUND JOURNAL (2017)

Add to Collection

Article Biochemistry & Molecular Biology

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

Lauren Radlinski et al.

PLOS BIOLOGY (2017)

Add to Collection

Review Immunology

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

M. Fata Moradali et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)

Add to Collection

Article Dermatology

The prevalence of biofilms in chronic wounds: a systematic review and meta-analysis of published data

M. Malone et al.

JOURNAL OF WOUND CARE (2017)

Add to Collection

Review Microbiology

Biofilms: an emergent form of bacterial life

Hans-Curt Flemming et al.

NATURE REVIEWS MICROBIOLOGY (2016)

Add to Collection

Article Microbiology

Cystic Fibrosis Isolates of Pseudomonas aeruginosa Retain Iron-Regulated Antimicrobial Activity against Staphylococcus aureus through the Action of Multiple Alkylquinolones

Angela T. Nguyen et al.

FRONTIERS IN MICROBIOLOGY (2016)

Add to Collection

Article Dermatology

Clinical investigation of biofilm in non-healing wounds by high resolution microscopy techniques

J. Hurlow et al.

JOURNAL OF WOUND CARE (2016)

Add to Collection

Article Surgery

Microenvironment and microbiology of skin wounds: the role of bacterial biofilms and related factors

A. Scalise et al.

SEMINARS IN VASCULAR SURGERY (2015)

Add to Collection

Article Dermatology

Bacterial spectrum colonizing chronic leg ulcers: A 10-year comparison from a German wound care center

Finja Jockenhoefer et al.

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT (2014)

Add to Collection

Article Dermatology

Histopathology of body art revisited - analysis and discussion of 19 cases

Rebecca Koerner et al.

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT (2013)

Add to Collection

Article Microbiology

Three-Dimensional Human Skin Equivalent as a Tool To Study Acinetobacter baumannii Colonization

Anna de Breij et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)

Add to Collection

Review Microbiology

Biofilm-specific antibiotic resistance

Thien-Fah Mah

FUTURE MICROBIOLOGY (2012)

Add to Collection

Article Biotechnology & Applied Microbiology

Development and application of a polymicrobial, in vitro, wound biofilm model

J. Woods et al.

JOURNAL OF APPLIED MICROBIOLOGY (2012)

Add to Collection

Review Microbiology

Multi-species biofilms: living with friendly neighbors

Sivan Elias et al.

FEMS MICROBIOLOGY REVIEWS (2012)

Add to Collection

Article Endocrinology & Metabolism

Wound fluid lactate concentration: a helpful marker for diagnosing soft-tissue infection in diabetic foot ulcers? Preliminary findings

M. Loeffler et al.

DIABETIC MEDICINE (2011)

Add to Collection

Article Multidisciplinary Sciences

High-Level Fluorescence Labeling of Gram-Positive Pathogens

Simone Aymanns et al.

PLOS ONE (2011)

Add to Collection

Article Immunology

An in vitro model of bacterial infections in wounds and other soft tissues

Maria Werthen et al.

APMIS (2010)

Add to Collection

Review Microbiology

The biofilm matrix

Hans-Curt Flemming et al.

NATURE REVIEWS MICROBIOLOGY (2010)

Add to Collection

Article Dermatology

Testing wound dressings using an in vitro wound model

C. Lipp et al.

JOURNAL OF WOUND CARE (2010)

Add to Collection

Article Microbiology

Nonrandom Distribution of Pseudomonas aeruginosa and Staphylococcus aureus in Chronic Wounds

Mustafa Fazli et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2009)

Add to Collection

Article Biochemistry & Molecular Biology

A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence

C Vuong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.