☆ 4.7 Review

Human Gut Microbiota in Heart Failure: Trying to Unmask an Emerging Organ

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NATURE METABOLISM (2020)

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Effect of Saccharomyces boulardii CNCM I-745 as complementary treatment of Helicobacter pylori infection on gut microbiome

Paul A. Cardenas et al.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2020)

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Microbiome-Based Biomarkers for IBD

Ashwin N. Ananthakrishnan

INFLAMMATORY BOWEL DISEASES (2020)

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Proteomics and the microbiome: pitfalls and potential

Huafeng Lin et al.

EXPERT REVIEW OF PROTEOMICS (2019)

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Alterations in the gut microbiome and metabolism with coronary artery disease severity

Honghong Liu et al.

MICROBIOME (2019)

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Current understanding of gut microbiota alterations and related therapeutic intervention strategies in heart failure

Xi Chen et al.

CHINESE MEDICAL JOURNAL (2019)

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Gut Microbiome: A Promising Biomarker for Immunotherapy in Colorectal Cancer

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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Gut Microbiome and Response to Cardiovascular Drugs

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Metabolic signature of obesity-associated insulin resistance and type 2 diabetes

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Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women

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EUROPEAN HEART JOURNAL (2019)

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Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure: results from BIOSTAT-CHF

Toru Suzuki et al.

EUROPEAN JOURNAL OF HEART FAILURE (2019)

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Shared gut, but distinct oral microbiota composition in primary Sjogren's syndrome and systemic lupus erythematosus

Taco A. van der Meulen et al.

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Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload

Andrew J. Schwartz et al.

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Dietary metabolism, the gut microbiome, and heart failure

W. H. Wilson Tang et al.

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The Role of the Microbiome in Cancer Initiation and Progression: How Microbes and Cancer Cells Utilize Excess Energy and Promote One Another's Growth

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CURRENT NUTRITION REPORTS (2019)

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Article Cardiac & Cardiovascular Systems

Anemia and Iron Deficiency in Heart Failure: Current Concepts and Emerging Therapies

Inder S. Anand et al.

CIRCULATION (2018)

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Prevalence and prognostic impact of non-cardiac co-morbidities in heart failure outpatients with preserved and reduced ejection fraction: a community-based study

Annamaria Iorio et al.

EUROPEAN JOURNAL OF HEART FAILURE (2018)

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Letter Cardiac & Cardiovascular Systems

Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts

Martin Kummen et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

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Article Medicine, General & Internal

Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals

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LANCET (2018)

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The Effect of Different L-Carnitine Administration Routes on the Development of Atherosclerosis in ApoE Knockout Mice

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Article Biochemistry & Molecular Biology

Trimethylamine-N-Oxide (TMAO)-Induced Impairment of Cardiomyocyte Function and the Protective Role of Urolithin B-Glucuronide

Monia Savi et al.

MOLECULES (2018)

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Current understanding of the human microbiome

Jack A. Gilbert et al.

NATURE MEDICINE (2018)

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Contributory Role of Gut Microbiota and Their Metabolites Toward Cardiovascular Complications in Chronic Kidney Disease

Daniel Y. Li et al.

SEMINARS IN NEPHROLOGY (2018)

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Mediterranean Diet and Other Dietary Patterns in Primary Prevention of Heart Failure and Changes in Cardiac Function Markers: A Systematic Review

Karina Sanches Machado d'Almeida et al.

NUTRIENTS (2018)

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Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients

Xiao Cui et al.

SCIENTIFIC REPORTS (2018)

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Microbiome and Allergic Diseases

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FRONTIERS IN IMMUNOLOGY (2018)

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The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF

Nazir Savji et al.

JACC-HEART FAILURE (2018)

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Temporal Trends in the Incidence of and Mortality Associated With Heart Failure With Preserved and Reduced Ejection Fraction

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JACC-HEART FAILURE (2018)

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Dynamics of metatranscription in the inflammatory bowel disease gut microbiome

Melanie Schirmer et al.

NATURE MICROBIOLOGY (2018)

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Mechanisms and Treatments of Oxidative Stress in Atrial Fibrillation

Xiaomeng Ren et al.

CURRENT PHARMACEUTICAL DESIGN (2018)

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Extensive impact of non-antibiotic drugs on human gut bacteria

Lisa Maier et al.

NATURE (2018)

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Oral probiotic combination of Lactobacillus and Bifidobacterium alters the gastrointestinal microbiota during antibiotic treatment for Clostridium difficile infection

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PLOS ONE (2018)

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Gut Bacterial Microbiota and its Resistome Rapidly Recover to Basal State Levels after Shortterm Amoxicillin-Clavulanic Acid Treatment in Healthy Adults

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SCIENTIFIC REPORTS (2018)

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The impact of Helicobacter pylori infection, eradication therapy and probiotic supplementation on gut microenvironment homeostasis: An open-label, randomized clinical trial

Luyi Chen et al.

EBIOMEDICINE (2018)

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Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017

Spencer L. G. James et al.

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Interaction between gut microbiome and cardiovascular disease

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LIFE SCIENCES (2018)

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Meeting Abstract Cardiac & Cardiovascular Systems

QRS duration is associated with outcome in symptomatic HF patients. What about ACCF/AHA stages A and B? Data from the DAVID-Berg study

A. Andrea Pozzi et al.

EUROPEAN JOURNAL OF HEART FAILURE (2018)

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High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice

Francine Z. Marques et al.

CIRCULATION (2017)

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Role of gut microbiota in atherosclerosis

Annika Lindskog Jonsson et al.

NATURE REVIEWS CARDIOLOGY (2017)

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Targeting of microbe-derived metabolites to improve human health: The next frontier for drug discovery

J. Mark Brown et al.

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Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure

Cristiane C. K. Mayerhofer et al.

JOURNAL OF CARDIAC FAILURE (2017)

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Trimethylamine-N-oxide and Heart Failure With Reduced Versus Preserved Ejection Fraction

Katharina Schuett et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

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Article Immunology

Effects of anti-Helicobacter pylori concomitant therapy and probiotic supplementation on the throat and gut microbiota in humans

Zi-Juan Wang et al.

MICROBIAL PATHOGENESIS (2017)

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Article Biochemistry & Molecular Biology

Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

Hao Wu et al.

NATURE MEDICINE (2017)

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Association between the gut microbiome and atherosclerosis

William T. Barrington et al.

NATURE REVIEWS CARDIOLOGY (2017)

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Human genetic variation and the gut microbiome in disease

Andrew Brantley Hall et al.

NATURE REVIEWS GENETICS (2017)

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Chemical transformation of xenobiotics by the human gut microbiota

Nitzan Koppel et al.

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The gut microbiome in atherosclerotic cardiovascular disease

Zhuye Jie et al.

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Novel Concept of a Heart-Gut Axis in the Pathophysiology of Heart Failure

Takehiro Kamo et al.

KOREAN CIRCULATION JOURNAL (2017)

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Gut microbiota dysbiosis contributes to the development of hypertension

Jing Li et al.

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Prospective randomized controlled study on the effects of &ITSaccharomyces boulardii&IT CNCM I-745 and amoxicillin-clavulanate or the combination on the gut microbiota of healthy volunteers

Toufic A. Kabbani et al.

GUT MICROBES (2017)

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Pathophysiology of Intestinal Na+/H+ Exchange

Michael A. Gurney et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2017)

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The coupling of taxonomy and function in microbiomes

S. Andrew Inkpen et al.

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The Origin and Diversification of Mitochondria

Andrew J. Roger et al.

CURRENT BIOLOGY (2017)

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2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America

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CIRCULATION (2017)

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Letter Cardiac & Cardiovascular Systems

Gut Microbe-Generated Trimethylamine N-Oxide From Dietary Choline Is Prothrombotic in Subjects

Weifei Zhu et al.

CIRCULATION (2017)

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Mining the Human Gut Microbiota for Immunomodulatory Organisms

Naama Geva-Zatorsky et al.

CELL (2017)

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Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure

Chelsea L. Organ et al.

CIRCULATION-HEART FAILURE (2016)

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Proton pump inhibitors affect the gut microbiome

Floris Imhann et al.

GUT (2016)

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Proton pump inhibitors alter the composition of the gut microbiota

Matthew A. Jackson et al.

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High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome

Francesca De Filippis et al.

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The Effect of Probiotics on Gut Microbiota during the Helicobacter pylori Eradication: Randomized Controlled Trial

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HELICOBACTER (2016)

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Exercise and gut immune function: evidence of alterations in colon immune cell homeostasis and microbiome characteristics with exercise training

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Physical activity in older age: perspectives for healthy ageing and frailty

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Atrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signal

Olurotimi O. Mesubi et al.

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Correction Biochemistry & Molecular Biology

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans (vol 165, pg 842, 2016)

Tommi Vatanen et al.

CELL (2016)

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Article Biochemistry & Molecular Biology

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

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CELL (2016)

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Trimethylamine N-oxide and prognosis in acute heart failure

Toru Suzuki et al.

HEART (2016)

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Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism

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MOLECULAR PSYCHIATRY (2016)

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Human gut microbes impact host serum metabolome and insulin sensitivity

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Diet-microbiota interactions as moderators of human metabolism

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The Human Intestinal Microbiome in Health and Disease

Susan V. Lynch et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity

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Machine Learning Meta-analysis of Large Metagenomic Datasets: Tools and Biological Insights

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Bacterial communities in penile skin, male urethra, and vaginas of heterosexual couples with and without bacterial vaginosis

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Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals

Christian Benedict et al.

MOLECULAR METABOLISM (2016)

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Altered fecal microbiota composition in patients with major depressive disorder

Haiyin Jiang et al.

BRAIN BEHAVIOR AND IMMUNITY (2015)

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Personalized Nutrition by Prediction of Glycemic Responses

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Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

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CELL HOST & MICROBE (2015)

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Intestinal Microbiota-Dependent Phosphatidylcholine Metabolites, Diastolic Dysfunction, and Adverse Clinical Outcomes in Chronic Systolic Heart Failure

W. H. Wilson Tang et al.

JOURNAL OF CARDIAC FAILURE (2015)

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Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

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ALLERGY Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

Martijn J. Schuijs et al.

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A Contemporary Appraisal of the Heart Failure Epidemic in Olmsted County, Minnesota, 2000 to 2010

Yariv Gerber et al.

JAMA INTERNAL MEDICINE (2015)

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Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation

Jill C. Gregory et al.

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Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure

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The Influence of Age and Gender on Skin-Associated Microbial Communities in Urban and Rural Human Populations

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Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney Disease

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CIRCULATION RESEARCH (2015)

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Human Genetics Shape the Gut Microbiome

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CELL (2014)

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Microbes, Microbiota, and Colon Cancer

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CELL HOST & MICROBE (2014)

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Determining Microbial Products and Identifying Molecular Targets in the Human Microbiome

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CELL METABOLISM (2014)

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Probiotic Administration Attenuates Myocardial Hypertrophy and Heart Failure After Myocardial Infarction in the Rat

Xiaohong Tracey Gan et al.

CIRCULATION-HEART FAILURE (2014)

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The heart and the gut

Gerhard Rogler et al.

EUROPEAN HEART JOURNAL (2014)

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Prevalence of unrecognized heart failure in older persons with shortness of breath on exertion

Evelien E. S. van Riet et al.

EUROPEAN JOURNAL OF HEART FAILURE (2014)

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Editorial Material Cardiac & Cardiovascular Systems

20 Things You Didn't Know About the Human Gut Microbiome

Erin P. Ferranti et al.

JOURNAL OF CARDIOVASCULAR NURSING (2014)

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Prognostic Value of Elevated Levels of Intestinal Microbe-Generated Metabolite Trimethylamine-N-Oxide in Patients With Heart Failure Refining the Gut Hypothesis

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The Uremic Toxicity of Indoxyl Sulfate and p-Cresyl Sulfate: A Systematic Review

Raymond Vanholder et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)

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Article Multidisciplinary Sciences

Diet rapidly and reproducibly alters the human gut microbiome

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NATURE (2014)

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Longitudinal analysis of microbial interaction between humans and the indoor environment

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Influence of a probiotic mixture on antibiotic induced microbiota disturbances

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WORLD JOURNAL OF GASTROENTEROLOGY (2014)

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Host lifestyle affects human microbiota on daily timescales

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A novel SCFA receptor, the microbiota, and blood pressure regulation

Jennifer L. Pluznick

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The gut in iron homeostasis: role of HIF-2 under normal and pathological conditions

Maria Mastrogiannaki et al.

BLOOD (2013)

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Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

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CELL HOST & MICROBE (2013)

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Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

Brian J. Bennett et al.

CELL METABOLISM (2013)

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Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury

Jun Pu et al.

EUROPEAN HEART JOURNAL (2013)

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Review Biochemistry & Molecular Biology

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

Gijs den Besten et al.

JOURNAL OF LIPID RESEARCH (2013)

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Article Biochemistry & Molecular Biology

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

Robert A. Koeth et al.

NATURE MEDICINE (2013)

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Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

W. H. Wilson Tang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

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The Microbiome in Infectious Disease and Inflammation

Kenya Honda et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)

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Gut microbiota composition correlates with diet and health in the elderly

Marcus J. Claesson et al.

NATURE (2012)

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Unlocking the potential of metagenomics through replicated experimental design

Rob Knight et al.

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Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

Anna C. Calkin et al.

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Microbes-induced EMT at the crossroad of inflammation and cancer

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GUT MICROBES (2012)

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The impact of perinatal immune development on mucosal homeostasis and chronic inflammation

Harald Renz et al.

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Multiple Facets of NF-κB in the Heart To Be or Not to NF-κB

Joseph W. Gordon et al.

CIRCULATION RESEARCH (2011)

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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Zeneng Wang et al.

NATURE (2011)

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Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

Ikuo Kimura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

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Article Biotechnology & Applied Microbiology

Moving pictures of the human microbiome

J. Gregory Caporaso et al.

GENOME BIOLOGY (2011)

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Article Microbiology

Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy

Anna Engelbrektson et al.

JOURNAL OF MEDICAL MICROBIOLOGY (2009)

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Article Critical Care Medicine

SYSTEMIC INFLAMMATION INCREASES INTESTINAL PERMEABILITY DURING EXPERIMENTAL HUMAN ENDOTOXEMIA

Falco Hietbrink et al.

SHOCK (2009)

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Article Gastroenterology & Hepatology

Farnesoid X Receptor Antagonizes Nuclear Factor κB in Hepatic Inflammatory Response

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HEPATOLOGY (2008)

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Farnesoid X receptor ligands inhibit vascular smooth muscle cell inflammation and migration

Yoyo T. Y. Li et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)

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The importance of the gastrointestinal system in the pathogenesis of heart failure

A Krack et al.

EUROPEAN HEART JOURNAL (2005)

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Article Infectious Diseases

Effects of probiotics on the composition of the intestinal microbiota following antibiotic therapy

SF Plummer et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2005)

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Effect of probiotics on preventing disruption of the intestinal microflora following antibiotic therapy: A double-blind, placebo-controlled pilot study

JAJ Madden et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2005)

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Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

NH Purcell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

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Use of biomarkers and surrogate endpoints in drug development and regulatory decision making: Criteria, validation, strategies

LJ Lesko et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2001)

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Article Pharmacology & Pharmacy

The effects of bile acids on β-adrenoceptors, fluidity, and the extent of lipid peroxidation in rat cardiac membranes

H Gazawi et al.

BIOCHEMICAL PHARMACOLOGY (2000)

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