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Is There a Relationship between Adverse Pregnancy Outcomes and Future Development of Atherosclerosis?

BIOMEDICINES (2023)

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Summary: This study used mendelian randomization to investigate the association between hypertensive disorders in pregnancy (HDPs) and multiple cardiovascular diseases. The results showed that HDPs were associated with an increased risk of coronary artery disease and ischemic stroke, and this association was partially mediated by cardiometabolic factors. Rating: 7/10.

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Summary: Previous studies have shown that women with a history of pregnancy loss have an increased risk of cardiovascular disease (CVD). This study analyzed the association between pregnancy loss history and incident CVD in postmenopausal women aged 50-79. The results showed that women with a history of stillbirth had an elevated risk of CVD within 5 years of study entry. This finding may have implications for clinical care.

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Perspectives on the Use of Placental Growth Factor (PlGF) in the Prediction and Diagnosis of Pre-Eclampsia: Recent Insights and Future Steps

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