4.7 Article

Paving the Way for Memory Enhancement: Development and Examination of a Neurofeedback System Targeting the Medial Temporal Lobe

Journal

BIOMEDICINES
Volume 11, Issue 8, Pages -

Publisher

MDPI
DOI: 10.3390/biomedicines11082262

Keywords

neurofeedback; memory enhancement; medial temporal lobe; intracranial electrode; bidirectional control; memory encoding; intracranial electroencephalogram; epilepsy

Ask authors/readers for more resources

This study aimed to develop a neurofeedback (NF) system for the memory function of the medial temporal lobe (MTL) and examine changes in neural activity and memory task scores through NF training. The results showed promising potential for NF to modulate MTL activity and memory encoding. Further research is needed to improve the NF system and validate its effects on memory functions.
Neurofeedback (NF) shows promise in enhancing memory, but its application to the medial temporal lobe (MTL) still needs to be studied. Therefore, we aimed to develop an NF system for the memory function of the MTL and examine neural activity changes and memory task score changes through NF training. We created a memory NF system using intracranial electrodes to acquire and visualise the neural activity of the MTL during memory encoding. Twenty trials of a tug-of-war game per session were employed for NF and designed to control neural activity bidirectionally (Up/Down condition). NF training was conducted with three patients with drug-resistant epilepsy, and we observed an increasing difference in NF signal between conditions (Up-Down) as NF training progressed. Similarities and negative correlation tendencies between the transition of neural activity and the transition of memory function were also observed. Our findings demonstrate NF's potential to modulate MTL activity and memory encoding. Future research needs further improvements to the NF system to validate its effects on memory functions. Nonetheless, this study represents a crucial step in understanding NF's application to memory and provides valuable insights into developing more efficient memory enhancement strategies.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available