☆ 4.7 Article

Synchronous Neoplasia Rates at Colonoscopic Diagnosis of Early-Onset vs Average-Onset Colorectal Cancer

JAMA NETWORK OPEN (2023)

Related references

Note: Only part of the references are listed.

Letter Gastroenterology & Hepatology

Adenoma Detection Rates for 45-to 49-Year-Old Screening Population

Aasma Shaukat et al.

GASTROENTEROLOGY (2022)

Add to Collection

Review Gastroenterology & Hepatology

Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis

Dylan E. O'Sullivan et al.

Summary: This study identified significant risk factors for early-onset colorectal cancer, including family history of colorectal cancer, hyperlipidemia, obesity, and alcohol consumption. Smoking was suggestive but not statistically significant as a risk factor. Other potential risk factors such as hypertension, metabolic syndrome, ulcerative colitis, and occupational exposure to organic dusts were also identified in limited studies. High-quality studies on generalizable populations are needed to further explore risk factors for early-onset colorectal cancer and inform prevention strategies.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2022)

Add to Collection

Article Gastroenterology & Hepatology

Age-Stratified Prevalence and Predictors of Neoplasia Among US Adults Undergoing Screening Colonoscopy in a National Endoscopy Registry

Peter S. Liang et al.

Summary: A study reveals that the prevalence of advanced colorectal neoplasia is higher in the 45-49 age group in the United States, supporting the recommendation to start screening at age 45. Men have a higher risk of neoplasia compared to women, and white individuals have a higher risk compared to other racial/ethnic groups. These findings have significant implications for adenoma detection and risk-based screening strategies.

GASTROENTEROLOGY (2022)

Add to Collection

Review Medicine, General & Internal

Increasing Incidence of Early-Onset Colorectal Cancer

Frank A. Sinicrope

Summary: Early-onset colorectal cancer, which accounts for 10% of cases, is increasing in incidence, particularly in high-income countries. Patients often present with advanced disease in the left colon, and one in six patients has deficient DNA mismatch repair. Screening is recommended to begin at 45 years of age.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

Add to Collection

Letter Gastroenterology & Hepatology

Clinically Significant Metachronous Colorectal Pathology Detected Among Young-Onset Colorectal Cancer Survivors: Implications for Post-Resection Surveillance Guidelines

Oliver Peacock et al.

GASTROENTEROLOGY (2022)

Add to Collection

Article Medicine, General & Internal

Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death

M. Bretthauer et al.

Summary: This randomized trial found that participants who were invited to undergo screening colonoscopy had a lower risk of colorectal cancer within 10 years.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

Add to Collection

Article Gastroenterology & Hepatology

Adenoma and Serrated Lesion Detection by Colonoscopy Indication: The ADR-ESS (ADR Extended to all Screening/Surveillance) Score

Uri Ladabaum et al.

Summary: A comprehensive, automated colonoscopy audit program was developed based on standardized clinical documentation, exploring detection rates across indications and developing the Adenoma Detection Rate - Extended to all Screening / Surveillance (ADR-ESS) score. This score increases the precision of adenoma detection assessments and emphasizes quality across colonoscopy indications.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

Add to Collection

Article Oncology

Metabolic Risk Factors Associated with Early-Onset Colorectal Adenocarcinoma: A Case-Control Study at Kaiser Permanente Southern California

Andrew J. Schumacher et al.

Summary: The study found a significant association between obesity and early-onset colorectal adenocarcinoma in individuals under age 50, while diabetes, hypertension, and dyslipidemia showed no significant association.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2021)

Add to Collection

Article Oncology

A Comprehensive Comparison of Early-Onset and Average-Onset Colorectal Cancers

Andrea Cercek et al.

Summary: The study found that patients with early-onset colorectal cancer are more likely to have left-sided tumors, present with rectal bleeding and abdominal pain, but are otherwise clinically and genomically indistinguishable from average-onset colorectal cancer. Aggressive treatment regimens based solely on the age at colorectal cancer diagnosis are not warranted.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

Add to Collection

Review Surgery

Characteristics of Early-Onset vs Late-Onset Colorectal Cancer A Review

Alexandra M. Zaborowski et al.

Summary: The incidence of early-onset colorectal cancer is increasing globally, with unique clinical, pathological, and molecular characteristics compared to late-onset disease. While genetic predisposition plays a role, most cases are sporadic and the full spectrum of implicated sequence variations remains unknown. Potential risk factors include a Westernized diet, obesity, antibiotic usage, and alterations in the gut microbiome. Despite early-onset patients being more likely to receive treatment, their oncological outcomes are comparable to older patients.

JAMA SURGERY (2021)

Add to Collection

Article Oncology

Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer

Alexi N. Archambault et al.

Summary: In this large study, several nongenetic risk factors associated with early-onset colorectal cancer were identified, providing a basis for targeted identification of high-risk individuals, which is crucial in mitigating the increasing burden of this disease.

JNCI CANCER SPECTRUM (2021)

Add to Collection

Article Oncology

Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer

Alexi N. Archambault et al.

Summary: This study found that early-onset colorectal cancer is associated with certain risk factors such as irregular use of nonsteroidal anti-inflammatory drugs, higher red meat intake, lower educational attainment, alcohol abstinence, and heavier alcohol use, with lower fiber intake being more strongly linked to rectal cancer. However, no risk factors showed a greater excess in early-onset compared to late-onset colorectal cancer.

JNCI CANCER SPECTRUM (2021)

Add to Collection

Article Medicine, General & Internal

Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence

Benjamin Click et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

Add to Collection

Article Oncology

Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer

Rachel Pearlman et al.

JAMA ONCOLOGY (2017)

Add to Collection

Review Oncology

Foods and beverages and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, an update of the evidence of the WCRF-AICR Continuous Update Project

A. R. Vieira et al.

ANNALS OF ONCOLOGY (2017)

Add to Collection

Article Gastroenterology & Hepatology

Advanced-Stage Colorectal Cancer in Persons Younger Than 50 Years Not Associated With Longer Duration of Symptoms or Time to Diagnosis

Frank W. Chen et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2017)

Add to Collection

Review Medicine, General & Internal

Colorectal Adenomas

Williamson B. Strum

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Add to Collection

Article Surgery

Increasing Disparities in the Age-Related Incidences of Colon and Rectal Cancers in the United States, 1975-2010

Christina E. Bailey et al.

JAMA SURGERY (2015)

Add to Collection

Article Pathology

Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression

Paul Lochhead et al.

MODERN PATHOLOGY (2015)

Add to Collection

Article Biotechnology & Applied Microbiology

Evidence for field effect cancerization in colorectal cancer

L. Hawthorn et al.

GENOMICS (2014)

Add to Collection

Review Medicine, Research & Experimental

Multifocal epithelial tumors and field cancerization: stroma as a primary determinant

G. Paolo Dotto

JOURNAL OF CLINICAL INVESTIGATION (2014)

Add to Collection

Article Gastroenterology & Hepatology

Variation of Adenoma Prevalence by Age, Sex, Race, and Colon Location in a Large Population: Implications for Screening and Quality Programs

Douglas A. Corley et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2013)

Add to Collection

Article Gastroenterology & Hepatology

Serrated Colon Polyps as Precursors to Colorectal Cancer

Seth Sweetser et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2013)

Add to Collection

Article Oncology

A Pooled Analysis of Smoking and Colorectal Cancer: Timing of Exposure and Interactions with Environmental Factors

Jian Gong et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2012)

Add to Collection

Article Pathology

Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features

Daniel T. Chang et al.

MODERN PATHOLOGY (2012)

Add to Collection

Article Medicine, General & Internal

Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths

Ann G. Zauber et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Add to Collection

Editorial Material Medicine, General & Internal

The flexible sigmoidoscopie can save lives

Helene Vaillant-Roussel et al.

EXERCER-LA REVUE FRANCOPHONE DE MEDECINE GENERALE (2012)

Add to Collection

Article Medicine, General & Internal

Colorectal-Cancer Incidence and Mortality with Screening Flexible Sigmoidoscopy

Robert E. Schoen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Add to Collection

Article Oncology

Association between monoallelic MUTYH mutation and colorectal cancer risk: a meta-regression analysis

Aung Ko Win et al.

FAMILIAL CANCER (2011)

Add to Collection

Article Multidisciplinary Sciences

Red and Processed Meat and Colorectal Cancer Incidence: Meta-Analysis of Prospective Studies

Doris S. M. Chan et al.

PLOS ONE (2011)

Add to Collection

Article Gastroenterology & Hepatology

T1091 Synchronous Neoplastic Lesions in Colorectal Cancer. Analysis of Possible Risk Factors Favouring Presentation

Ana Borda et al.

GASTROENTEROLOGY (2008)

Add to Collection

Article Biochemistry & Molecular Biology

Germline CHEK2 mutations and colorectal cancer risk:: different effects of a missense and truncating mutations?

Cezary Cybulski et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2007)

Add to Collection

Article Gastroenterology & Hepatology

Synchronous colorectal neoplasms in patients with colorectal cancer:: Predisposing individual and familial factors

V Piñol et al.

DISEASES OF THE COLON & RECTUM (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.