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Microfluidics Coupled Mass Spectrometry for Single Cell Multi-Omics

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3D-Printed High-Density Droplet Array Chip for Miniaturized Protein Crystallization Screening under Vapor Diffusion Mode

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NATURE REVIEWS DRUG DISCOVERY (2016)

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Highly efficient and gentle trapping of single cells in large microfluidic arrays for time-lapse experiments

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BIOMICROFLUIDICS (2016)

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Single-cell isolation by a modular single-cell pipette for RNA-sequencing

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Deterministic sequential isolation of floating cancer cells under continuous flow

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LAB ON A CHIP (2016)

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Study of Phospholipids in Single Cells Using an Integrated Microfluidic Device Combined with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

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ANALYTICAL CHEMISTRY (2015)

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Article Chemistry, Analytical

Energy Charge, Redox State, and Metabolite Turnover in Single Human Hepatocytes Revealed by Capillary Microsampling Mass Spectrometry

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A microfluidic device enabling high-efficiency single cell trapping

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BIOMICROFLUIDICS (2015)

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Printing 2-Dimentional Droplet Array for Single-Cell Reverse Transcription Quantitative PCR Assay with a Microfluidic Robot

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SCIENTIFIC REPORTS (2015)

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The Single-Probe: A Miniaturized Multifunctional Device for Single Cell Mass Spectrometry Analysis

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ANALYTICAL CHEMISTRY (2014)

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In Vivo Imaging of Infection Using a Bacteria-Targeting Optical Nanoprobe

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JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2014)

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Article Multidisciplinary Sciences

Nanoliter-Scale Protein Crystallization and Screening with a Microfluidic Droplet Robot

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SCIENTIFIC REPORTS (2014)

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Sequential Operation Droplet Array: An Automated Microfluidic Platform for Picoliter-Scale Liquid Handling, Analysis, and Screening

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ANALYTICAL CHEMISTRY (2013)

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Microfluidic integrated optoelectronic tweezers for single-cell preparation and analysis

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Mass spectrometry-based metabolomics of single yeast cells

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Review Multidisciplinary Sciences

Single-Cell Metabolomics: Analytical and Biological Perspectives

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Article Biochemical Research Methods

Trapping cells on a stretchable microwell array for single-cell analysis

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ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2012)

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Single Cell Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

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Optofluidic integrated cell sorter fabricated by femtosecond lasers

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NATURE NANOTECHNOLOGY (2012)

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Microfluidic fluorescence in situ hybridization and flow cytometry (mu FlowFISH)

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Enhanced cell sorting and manipulation with combined optical tweezer and microfluidic chip technologies

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A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells

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NATURE MEDICINE (2011)

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Single-Cell MALDI-MS as an Analytical Tool for Studying Intrapopulation Metabolic Heterogeneity of Unicellular Organisms

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ANALYTICAL CHEMISTRY (2010)

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Femtosecond laser fabricated monolithic chip for optical trapping and stretching of single cells

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OPTICS EXPRESS (2010)

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Interfacing Microfluidics and Laser Desorption/Ionization Mass Spectrometry by Continuous Deposition for Application in Single Cell Analysis

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CHIMIA (2009)

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Microvalve-actuated precise control of individual droplets in microfluidic devices

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A trap-and-release integrated microfluidic system for dynamic microarray applications

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

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Single-cell enzyme concentrations, kinetics, and inhibition analysis using high-density hydrodynamic cell isolation arrays

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ANALYTICAL CHEMISTRY (2006)

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Article Biotechnology & Applied Microbiology

Antibody-based nanoprobe for measurement of a fluorescent analyte in a single cell

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