4.7 Article

The past, present and future of microbiome analyses

Journal

NATURE PROTOCOLS
Volume 11, Issue 11, Pages 4-8

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nprot.2016.148

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Funding

  1. Pan-omics Program - US Department of Energy's Office of Biological and Environmental Research (Genomic Science Program)
  2. Microbiomes in Transition (MinT) Laboratory Directed Research and Development Initiative at the Pacific Northwest National Laboratory
  3. Department of Energy [DE-AC06-76RL01830]

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Over the last decade, technical advances in nucleic acid sequencing and mass spectrometry have enabled faster and more informative metagenomic, metatranscriptomic, metaproteomic and metabolomic measurements. Here we review key improvements in multi-omic environmental and human microbiome analyses, and discuss developments required to address current measurement shortcomings.

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