4.7 Article

Differences in the Electric Field Distribution Predicted with a Mathematical Model of Cylindrical Electrodes of Finite Length vs. Infinite Length: A Comparison Based on Analytical Solution

Related references

Note: Only part of the references are listed.
Review Chemistry, Physical

Electrical Stimulation and Cellular Behaviors in Electric Field in Biomedical Research

Shiyun Meng et al.

Summary: This work reviews the research on the cellular response to electrical stimulation (ES) and its mechanisms, focusing on potential clinical applications. Different techniques and methodologies have been developed, leading to complications in interpreting and comparing experimental outcomes. The review categorizes these techniques and comments on their strengths and weaknesses. The study finds that ES can enhance cell proliferation, growth, migration, and stem cell differentiation, showing potential for manipulating cellular activities. However, inappropriate parameters or setup can have negative effects, and comparing different parameter sets is challenging. Mechanistic studies are rare and much needed. Despite this, ES combined with advanced materials and nanotechnology is gaining momentum in biomedical research and regenerative medicine.

MATERIALS (2022)

Article Computer Science, Interdisciplinary Applications

Full torso and limited-domain computer models for epicardial pulsed electric field ablation

Ana Gonzalez-Suarez et al.

Summary: This study aimed to assess the electric field distribution in the heart and its surroundings during epicardial monopolar PEF ablation. The results showed that the electric field was mainly limited to the target area in the heart, and negligible in adjacent organs. The limited-domain model provided similar results to the full torso model in evaluating the electric field distribution.

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2022)

Article Biotechnology & Applied Microbiology

Pulsed Electric Field Ablation of Epicardial Autonomic Ganglia: Computer Analysis of Monopolar Electric Field across the Tissues Involved

Ana Gonzalez-Suarez et al.

Summary: The study aimed to investigate the distribution of electric field in tissues (fat, ganglionated plexi, myocardium, and blood) during epicardial pulsed electric field (PEF) ablation. The findings showed that PEF ablation mainly affected the epicardial fat layer, with minimal impact on the myocardium. The presence of saline on the epicardial fat surface resulted in lateral spread of the PEF zone around the electrode. The thickness of the fat layer and the presence of ganglionated plexi altered the distribution of the electric field.

BIOENGINEERING-BASEL (2022)

Article Cardiac & Cardiovascular Systems

In Silico Modelling to Assess the Electrical and Thermal Disturbance Provoked by a Metal Intracoronary Stent during Epicardial Pulsed Electric Field Ablation

Ana Gonzalez-Suarez et al.

Summary: The effect of metal intracoronary stents on PEF ablation was assessed. The presence of the coronary artery distorts the E-field distribution, but has minimal impact on the PEF-zone. Despite the presence of E-field hot spots, the temperature increase in the tissue is moderate.

JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2022)

Review Biochemistry & Molecular Biology

Cell death due to electroporation - A review

Tina Batista Napotnik et al.

Summary: Exposure of cells to high voltage electric pulses can transiently increase membrane permeability through electroporation. Electroporation can be reversible and used in gene transfer and drug delivery, but may also lead to irreversible electroporation causing cell death. Understanding the mechanisms of cell death and membrane repair after electroporation is crucial for optimizing and developing new techniques in medicine, biotechnology, and food technology.

BIOELECTROCHEMISTRY (2021)

Article Engineering, Biomedical

Improvements on spatial coverage and focality of deep brain stimulation in pre-surgical epilepsy mapping

Santiago Collavini et al.

Summary: Our study investigates the use of different SEEG electrodes for electrical stimulation mapping (x-DESM), proposing a novel strategy to increase the versatility of DESM. We demonstrate in a clinical case that x-DESM can replicate the full semiology of an epilepsy seizure with very low-intensity current injection, compared to typical adjacent DESM.

JOURNAL OF NEURAL ENGINEERING (2021)

Article Engineering, Multidisciplinary

Analytical transient-time solution for temperature in non perfused tissue during radiofrequency ablation

Juan A. Lopez Molina et al.

APPLIED MATHEMATICAL MODELLING (2017)

Article Engineering, Biomedical

Modeling of electric field distribution in tissues during electroporation

Selma Corovic et al.

BIOMEDICAL ENGINEERING ONLINE (2013)

Article Mathematics, Applied

High-precision evaluation of the Bessel functions via Hadamard series

R. B. Paris

JOURNAL OF COMPUTATIONAL AND APPLIED MATHEMATICS (2009)

Article Biochemical Research Methods

Analytical electric field and sensitivity analysis for two microfluidic impedance cytometer designs

T. Sun et al.

IET NANOBIOTECHNOLOGY (2007)

Article Engineering, Biomedical

Electric field of a six-needle array electrode used in drug and DNA delivery in vivo:: Analytical versus numerical solution

SB Dev et al.

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING (2003)

Article Engineering, Biomedical

Hepatic radiofrequency ablation with internally cooled probes: Effect of coolant temperature on lesion size

D Haemmerich et al.

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING (2003)

Article Engineering, Biomedical

Finite-element modeling of needle electrodes in tissue from the perspective of frequent model computation

D Sel et al.

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING (2003)