Journal
FRONTIERS IN VETERINARY SCIENCE
Volume 10, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fvets.2023.1248879
Keywords
immunocastration; surgical castration; male animal; animal welfare; GnRH
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Traditional methods of castration in animals have welfare issues, while GnRH immunocastration, as an animal-friendly alternative, effectively addresses these issues. This review systematically summarizes the principles, development, current applications, and challenges of GnRH immunocastration, offering insights into its role in promoting animal welfare.
Castration of male animals is intended to produce high-enhance quality of animal meat, prevent unpleasant taste, reduce aggressive behavior, and manage overbreeding. Over the years, Tranditional methods of mechanical and surgical castration have been employed over the years, but they fall short of meeting animal welfare requirements due to the associated risk of infection, pain, and stress. Immunocastration, specifically Gonadotropin-releasing hormone (GnRH)-immunocastration, targeting the hypothalamic-pituitary-testis (HPT) axis, has emerged as an animal-friendly alternative to surgical castration, effectively addressing these issues. This review seeks to systematically summarize the principles, development, current applications and challenges of GnRH-immunocastration, offering insights into its role in promoting animal welfare.
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