☆ 4.6 Review

Current Data and New Insights into the Genetic Factors of Atherogenic Dyslipidemia Associated with Metabolic Syndrome

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The clinical value of metabolic syndrome and risks of cardiometabolic events and mortality in the elderly: the Rotterdam study

Thijs T. W. van Herpt et al.

CARDIOVASCULAR DIABETOLOGY (2016)

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Review Biochemistry & Molecular Biology

Metabolic syndrome: genetic insights into disease pathogenesis

Maen D. Abou Ziki et al.

CURRENT OPINION IN LIPIDOLOGY (2016)

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Weight-Loss Diets, Adiponectin, and Changes in Cardiometabolic Risk in the 2-Year POUNDS Lost Trial

Wenjie Ma et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)

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Familial defective apolipoprotein B-100: A review

Lars H. Andersen et al.

JOURNAL OF CLINICAL LIPIDOLOGY (2016)

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Review Cardiac & Cardiovascular Systems

Type III Hyperlipoproteinemia: Still Worth Considering?

Conrad B. Blum

PROGRESS IN CARDIOVASCULAR DISEASES (2016)

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Article Multidisciplinary Sciences

Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome

Yanhua Wu et al.

PLOS ONE (2016)

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The Distribution of Apolipoprotein E Gene Polymorphism and Apolipoprotein E Levels among Coronary Artery Patients Compared to Controls

Omer Atis et al.

EURASIAN JOURNAL OF MEDICINE (2016)

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Article Endocrinology & Metabolism

ATP-binding cassette transporter A1 (ABCA1) R219K (G1051A, rs2230806) polymorphism and serum high-density lipoprotein cholesterol levels in a large Japanese population: cross-sectional data from the Daiko Study

Junichiro Mokuno et al.

ENDOCRINE JOURNAL (2015)

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Article Biochemistry & Molecular Biology

The Apolipoprotein A1 polymorphisms were associated with decreased risk for metabolic syndrome in Koreans

Young Ree Kim et al.

GENES & GENOMICS (2015)

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Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

Mary K. Wojczynski et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2015)

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Article Medicine, General & Internal

Prevalence, associated factors and heritabilities of metabolic syndrome and its individual components in African Americans: the Jackson Heart Study

Rumana J. Khan et al.

BMJ OPEN (2015)

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Relation between ADIPOQ Gene Polymorphisms and Type 2 Diabetes

Zhi-Peng Li et al.

GENES (2015)

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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

Ron Do et al.

NATURE (2015)

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Article Cardiac & Cardiovascular Systems

Metabolic syndrome across Europe: Different clusters of risk factors

Angelo Scuteri et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2015)

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Article Endocrinology & Metabolism

Apolipoprotein B Is Related to Metabolic Syndrome Independently of Low Density Lipoprotein Cholesterol in Patients with Type 2 Diabetes

Younghyup Lim et al.

ENDOCRINOLOGY AND METABOLISM (2015)

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Article Hematology

Specific macrothrombocytopenia/hemolytic anemia associated with sitosterolemia

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AMERICAN JOURNAL OF HEMATOLOGY (2014)

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Genetic Evidence for a Normal-Weight Metabolically Obese Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes

Hanieh Yaghootkar et al.

DIABETES (2014)

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Article Multidisciplinary Sciences

Rs964184 (APOA5-A4-C3-A1) Is Related to Elevated Plasma Triglyceride Levels, but Not to an Increased Risk for Vascular Events in Patients with Clinically Manifest Vascular Disease

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PLOS ONE (2014)

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Review Endocrinology & Metabolism

Genetics of metabolic syndrome

Alena Stancakova et al.

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2014)

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A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans

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NATURE COMMUNICATIONS (2014)

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Article Genetics & Heredity

Genetic association of ADIPOQ gene variants with type 2 diabetes, obesity and serum adiponectin levels in south Indian population

Kandaswamy Ramya et al.

GENE (2013)

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Identification and biochemical analysis of a novel APOB mutation that causes autosomal dominant hypercholesterolemia

Ellen R. A. Thomas et al.

MOLECULAR GENETICS & GENOMIC MEDICINE (2013)

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The role of lecithin:cholesterol acyltransferase in the modulation of cardiometabolic risks - A clinical update and emerging insights from animal models

Dominic S. Ng

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)

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Article Cardiac & Cardiovascular Systems

Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution But No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

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CIRCULATION-CARDIOVASCULAR GENETICS (2012)

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Article Biotechnology & Applied Microbiology

Association of the HindIII and S447X polymorphisms in LPL gene with hypertension and type 2 diabetes in Mexican families

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DISEASE MARKERS (2012)

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Approach to the Patient with Extremely Low HDL-Cholesterol

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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

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Population-Based Resequencing of APOA1 in 10,330 Individuals: Spectrum of Genetic Variation, Phenotype, and Comparison with Extreme Phenotype Approach

Christiane L. Haase et al.

PLOS GENETICS (2012)

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A Bivariate Genome-Wide Approach to Metabolic Syndrome STAMPEED Consortium

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DIABETES (2011)

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Genetic variants in lipid metabolism are independently associated with multiple features of the metabolic syndrome

Cecile M. Povel et al.

LIPIDS IN HEALTH AND DISEASE (2011)

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Biological, clinical and population relevance of 95 loci for blood lipids

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NATURE (2010)

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A Genome-Wide Association Study of the Metabolic Syndrome in Indian Asian Men

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PLOS ONE (2010)

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Harmonizing the Metabolic Syndrome A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity

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CIRCULATION (2009)

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Association of Adiponectin Gene Polymorphisms With Type 2 Diabetes in an African American Population Enriched for Nephropathy

Meredith A. Bostrom et al.

DIABETES (2009)

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Article Cardiac & Cardiovascular Systems

The Linosa Study: Epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate

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NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2009)

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Article Biotechnology & Applied Microbiology

Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the Genetics of Lipid-Lowering Drugs and Diet Network study

Yongjun Liu et al.

PHARMACOGENETICS AND GENOMICS (2009)

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Genetics of Metabolic Syndrome

Tisha Joy et al.

CURRENT DIABETES REPORTS (2008)

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A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2

K. Hoffmann et al.

DIABETOLOGIA (2007)

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Coincident linkage of type 2 diabetes, metabolic syndrome, and measures of cardiovascular disease in a genome scan of the Diabetes Heart Study

Donald W. Bowden et al.

DIABETES (2006)

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Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

JC Cohen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

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Interaction of the-308G/A promoter polymorphism of the tumor necrosis factor-alpha gene with single-nucleotide polymorphism 45 of the adiponectin gene: Effect on serum adiponectin concentrations in a Spanish population

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CLINICAL CHEMISTRY (2006)

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Review Cardiac & Cardiovascular Systems

Genetic determinants of the metabolic syndrome

Rebecca L. Pollex et al.

NATURE CLINICAL PRACTICE CARDIOVASCULAR MEDICINE (2006)

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Genetic contributors toward increased risk for ischemic heart disease

MA Nordlie et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2005)

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Heritabilities of the metabolic syndrome and its components in the Northern Manhattan Family Study

HF Lin et al.

DIABETOLOGIA (2005)

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Linkage of the metabolic syndrome to 1q23-q31 in hispanic families - The Insulin Resistance Atherosclerosis Study Family Study

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DIABETES (2004)

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Associations between serum high-density lipoprotein cholesterol or apolipoprotein AI levels and common genetic variants of the ABCA1 gene in Japanese school-aged children

K Yamakawa-Kobayashi et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2004)

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The S447X polymorphism of the lipoprotein lipase gene is associated with lipoprotein lipid and blood pressure levels in Chinese patients with essential hypertension

AP Liu et al.

JOURNAL OF HYPERTENSION (2004)

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Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia

S Eichenbaum-Voline et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)

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Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25

MCY Ng et al.

DIABETES (2004)

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Lipoprotein lipase gene polymorphisms and blood pressure levels in the northern Chinese han population

B Li et al.

HYPERTENSION RESEARCH (2004)

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Hypoadiponectinemia is an independent risk factor for hypertension

Y Iwashima et al.

HYPERTENSION (2004)

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A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia

JT Kao et al.

HUMAN MOLECULAR GENETICS (2003)

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Coronary artery disease risk in familial combined - Hyperlipidemia and familial hypertriglyceridemia - A case-control comparison from the National Heart, Lung, and Blood Institute Family Heart Study

PN Hopkins et al.

CIRCULATION (2003)

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Article Biochemistry & Molecular Biology

Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians

F Vasseur et al.

HUMAN MOLECULAR GENETICS (2002)

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Apolipoprotein E polymorphism and cardiovascular disease: A HuGE review

JE Eichner et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2002)

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Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH:: a clinical and molecular genetic analysis

M Arca et al.

LANCET (2002)

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Apolipoprotein A-IMilano and apolipoprotein A-IParis exhibit an antioxidant activity distinct from that of wild-type apolipoprotein A-I

JK Bielicki et al.

BIOCHEMISTRY (2002)

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Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population

K Hara et al.

DIABETES (2002)

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Prevalence of the metabolic syndrome among US adults - Findings from the Third National Health and Nutrition Examination Survey

ES Ford et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)

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Factors of insulin resistance syndrome-related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic Mexican-Americans

R Arya et al.

DIABETES (2002)

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The LPL S447X cSNP is associated with decreased blood pressure and plasma triglycerides, and reduced risk of coronary artery disease

SM Clee et al.

CLINICAL GENETICS (2001)

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Apolipoprotein E4 and coronary heart disease in middle-aged men who smoke: a prospective study

SE Humphries et al.

LANCET (2001)

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Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome

AH Kissebah et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

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Article Peripheral Vascular Disease

Lipoprotein lipase (C/G)447 polymorphism and blood pressure in the Stanislas Cohort

G Sass et al.

JOURNAL OF HYPERTENSION (2000)

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Substitution of asparagine for aspartic acid at residue 9 (D9N) of lipoprotein lipase markedly augments risk of ischaemic heart disease in male smokers

PJ Talmud et al.

ATHEROSCLEROSIS (2000)

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