4.7 Article

Solarplast(& REG;)-An Enzymatically Treated Spinach Extract

Related references

Note: Only part of the references are listed.
Review Integrative & Complementary Medicine

Effects of antioxidants on diabetic kidney diseases: mechanistic interpretations and clinical assessment

Yuting Sun et al.

Summary: Diabetic kidney disease (DKD) is more common in individuals with diabetes mellitus and often involves oxidative stress. This study aimed to explore the impact of oxidative stress on DKD, conduct a systematic review and meta-analysis, and examine the effects of antioxidants on the disease. Analysis of 19 randomized controlled trials found that antioxidants were effective in reducing albumin excretion rate, urine albumin/creatinine ratio, glycated hemoglobin, and malonaldehyde levels in patients with DKD. These findings suggest that antioxidants may have therapeutic benefits for DKD, particularly in reducing proteinuria and glycated hemoglobin levels. The study offers new insights for drug research and clinical treatment of DKD.

CHINESE MEDICINE (2023)

Article Biochemistry & Molecular Biology

Dietary Antioxidants, Quality of Nutrition and Cardiovascular Characteristics among Omnivores, Flexitarians and Vegetarians in Poland-The Results of Multicenter National Representative Survey WOBASZ

Magdalena Kwasniewska et al.

Summary: Several reports reveal that plant-based diets provide higher antioxidant intake compared to meat-rich diets. However, data on dietary patterns and cardiovascular disease prevention in Central and Eastern Europe are limited. This study aimed to assess nutrition quality and cardiovascular characteristics in Polish adults following different diets. The results showed that neither flexitarians nor vegetarians had better dietary habits compared to omnivores, and omnivores had higher intake of natural antioxidants. The study suggests the need for guidance on balanced nutrition for Polish adults.

ANTIOXIDANTS (2023)

Review Biochemistry & Molecular Biology

Oxidative Stress, Antioxidants and Hypertension

Michael Amponsah-Offeh et al.

Summary: Hypertension is a major global health threat, and despite the availability of antihypertensive medications, resistance to treatment remains a problem. The renin-angiotensin-aldosterone system, immune system activation, and oxidative stress have been implicated in hypertension's pathogenesis. In addition to standard antihypertensive medications, antioxidants have been tested as a potential treatment. This review discusses the role of oxidative stress in hypertension and explores the use of antioxidants in its management.

ANTIOXIDANTS (2023)

Article Biochemistry & Molecular Biology

Carotenoids Composition of Green Algae Caulerpa racemosa and Their Antidiabetic, Anti-Obesity, Antioxidant, and Anti-Inflammatory Properties

Rudy Kurniawan et al.

Summary: This study aimed to investigate the carotenoid profile and biological activities of Caulerpa racemosa. The results showed that the detected carotenoids were mainly xanthophylls, including beta-carotene, lutein, astaxanthin, canthaxanthin, zeaxanthin, beta-cryptoxanthin, and fucoxanthin. The carotenoid extract of C. racemosa exhibited significant antidiabetic, anti-obesity, anti-oxidative, anti-inflammatory, and cytotoxic activities, making it a potential candidate for drug development or functional food.

MOLECULES (2023)

Review Pharmacology & Pharmacy

Acetaminophen-induced liver injury: Molecular mechanism and treatments from natural products

Jiaqing Liao et al.

Summary: Acetaminophen (APAP) is a widely used analgesic and antipyretic medicine. However, APAP overdose can lead to liver damage and acute liver failure. Natural products, such as polyphenols and terpenes, have been found to activate the liver's antioxidant defense system and protect against oxidative stress caused by APAP. The cytochrome P450 enzymes, which metabolize APAP into a toxic compound, are also considered as potential targets for treating APAP-induced liver injury. This review provides valuable information for future studies and trials on the use of natural products for preventing APAP-induced liver toxicity.

FRONTIERS IN PHARMACOLOGY (2023)

Review Biochemistry & Molecular Biology

Current Status of Obesity: Protective Role of Catechins

Tanisha Basu et al.

Summary: Obesity is a growing health concern in society, affecting both adults and young people. Recent research revealed a higher likelihood of overweight in the Hispanic population compared to non-Hispanic individuals. Obesity is a multifactorial disease with various causes, including genetics, biochemistry, psychology, environment, behavior, and socio-demographics. It leads to serious health problems and involves cellular changes such as mitochondrial dysfunction, deregulated microRNAs, inflammation, and hormonal imbalances. This article highlights the role of oxidative stress in obesity and discusses the impact of catechins on prevention and treatment.

ANTIOXIDANTS (2023)

Article Chemistry, Medicinal

In vitro enzymatic evaluation of some pyrazolo[1,5-a]pyrimidine derivatives: Design, synthesis, antioxidant, anti-diabetic, anti-Alzheimer, and anti-arthritic activities with molecular modeling simulation

Ashraf S. Hassan et al.

Summary: The strategy of using nitrogen compounds in biological applications has proven to be effective in developing novel therapeutic drugs. A series of pyrazolo[1,5-a]pyrimidine compounds were synthesized and evaluated for their biological activities, with three compounds being identified as the most active derivatives.

DRUG DEVELOPMENT RESEARCH (2023)

Article Multidisciplinary Sciences

Computational, chemical profile, in vitro antioxidant, hypoglycaemic, and anti-inflammatory activity of hexane extract of some selected dark green vegetables

Emmanuel U. Ejiofor et al.

Summary: This study investigated the phytochemical composition and potential antioxidant, hypoglycemic, and anti-inflammatory activities of n-hexane extracts from Vernonia amygdalina (VA), Telfairia occidentalis (TO), Gongronema latifolium (GL), and Ocimum gratissimum (OG). The extracts showed concentration-dependent increase in antioxidant activity. TO exhibited significantly higher antioxidant activity compared to the other extracts, while GL had the highest total phenolic content and OG had the highest total flavonoid content. The extracts also demonstrated hypoglycemic and anti-inflammatory effects, which could be attributed to the presence of identified phytocompounds.

PROCEEDINGS OF THE INDIAN NATIONAL SCIENCE ACADEMY (2023)

Article Biochemical Research Methods

Optimization of protoplast regeneration in the model plant Arabidopsis thaliana

Yeong Yeop Jeong et al.

Summary: The study optimized a cell and tissue culture system for protoplast regeneration in Arabidopsis thaliana, with highest potential observed in Ws-2 ecotype. By applying a modified thin alginate layer, protoplasts were cultured at an optimal density of 1 x 10(6) protoplasts/mL, leading to successful callus formation and de novo shoot regeneration. The regenerated plants were fertile and able to produce normal progenies, highlighting the efficiency and reproducibility of the method for fundamental studies on pluripotency establishment and de novo tissue regeneration.

PLANT METHODS (2021)

Article Biochemistry & Molecular Biology

Antioxidants, Food Processing and Health

Borut Poljsak et al.

Summary: The article discusses the impact of oxidized forms of natural antioxidants on health during food processing, highlighting their role in cell signaling, gene expression, and potential health benefits through activation of damage repair processes and antioxidative defense systems. Additionally, it points out the importance of functional studies to understand the effects of antioxidants on organisms and the potential synergistic effects of reduced or oxidized antioxidants and their metabolites.

ANTIOXIDANTS (2021)

Article Food Science & Technology

Biological Effect of Different Spinach Extracts in Comparison with the Individual Components of the Phytocomplex

Laura Arru et al.

Summary: The research found that spinach extracts and the components of the phytocomplex have certain regulatory effects on the proliferation, antioxidant defense, and genotoxicity of human colorectal cells, with a certain dose-dependent and extraction method-related correlation. In the presence of oxidative stress, their effects vary depending on the specific oxidizing agent involved.

FOODS (2021)

Review Biology

Oxidative stress, nutritional antioxidants and beyond

Qiuping Guo et al.

SCIENCE CHINA-LIFE SCIENCES (2020)

Review Food Science & Technology

Plant Cell Walls: Impact on Nutrient Bioaccessibility and Digestibility

Claire Holland et al.

FOODS (2020)

Article Multidisciplinary Sciences

Subcellular compartmentalization of the plant antioxidant system: an integrated overview

Aleksandr Bobrovskikh et al.

PEERJ (2020)

Review Physiology

Role of ROS and Nutritional Antioxidants in Human Diseases

Zewen Liu et al.

FRONTIERS IN PHYSIOLOGY (2018)

Review Cell Biology

Oxidative Stress: Harms and Benefits for Human Health

Gabriele Pizzino et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Review Public, Environmental & Occupational Health

Antioxidants: Friend or foe?

R. Sarangarajan et al.

ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE (2017)

Review Biochemistry & Molecular Biology

Functional properties of spinach (Spinacia oleracea L.) phytochemicals and bioactives

Joseph L. Roberts et al.

FOOD & FUNCTION (2016)

Article Peripheral Vascular Disease

Evolving Concepts of Oxidative Stress and Reactive Oxygen Species in Cardiovascular Disease

Kai Chen et al.

CURRENT ATHEROSCLEROSIS REPORTS (2012)

Review Gastroenterology & Hepatology

Oxidative stress and liver disease

Runzhi Zhu et al.

HEPATOLOGY RESEARCH (2012)

Article Biotechnology & Applied Microbiology

Effect of enzyme concentrations on protoplast isolation and protoplast culture of Spathiphyllum and Anthurium

Barbara Duquenne et al.

PLANT CELL TISSUE AND ORGAN CULTURE (2007)

Article Biochemical Research Methods

Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis

Sang-Dong Yoo et al.

NATURE PROTOCOLS (2007)

Article Agriculture, Multidisciplinary

Antioxidant and anti proliferative activities of common vegetables

YF Chu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

The antioxidant activity of aqueous spinach extract: chemical identification of active fractions

M Bergman et al.

PHYTOCHEMISTRY (2001)

Article Agriculture, Multidisciplinary

Isolation and characterization of structurally novel antimutagenic flavonoids from spinach (Spinacia oleracea)

R Edenharder et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2001)