Journal
CLINICAL KIDNEY JOURNAL
Volume -, Issue -, Pages -Publisher
OXFORD UNIV PRESS
DOI: 10.1093/ckj/sfad163
Keywords
chronic kidney disease; clinical studies; sex equity
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Clinical studies often have an insufficient proportion of female participants, leading to a lack of sex-specific research data. This article highlights the gender imbalance in clinical studies, including those involving patients with chronic kidney disease. The absence of sex equity in research is a significant public health problem, as it hinders understanding of how drugs work differently in men and women. It is crucial to conduct further research on sex disparities in clinical studies to address the underrepresentation of women and promote gender equality in research.
Clinical studies do not include an adequate proportion of female participants, and research data on drug efficacy and safety are generally collected from studies including a majority of men and extrapolated to women. This article describes the imbalance of male and female distribution in clinical studies, including patients with chronic kidney disease. The lack of sex equity in clinical research is a real 'public health problem' because not reporting sex-specific results may result in the loss of information on how a drug works according to sex. Therefore, it is essential to plan more research in the field of sex disparities in clinical studies to identify why women are underrepresented and to promote initiatives to expand women's participation in clinical studies.
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