4.7 Review

Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms

Journal

FOODS
Volume 12, Issue 13, Pages -

Publisher

MDPI
DOI: 10.3390/foods12132529

Keywords

ergosterol; nutrition; food chemistry; bioactive compound; nutraceutical

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Ergosterol, a sterol found in edible mushrooms, is not only a precursor to vitamin D2 but also exhibits various pharmacological effects, such as antimicrobial, antioxidant, anticancer, antidiabetic, and anti-neurodegenerative activities. This review provides an overview of the pharmacological effects of ergosterol, its underlying mechanisms, and potential applications.
Ergosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that is converted to vitamin D2 under ultraviolet radiation. The pharmacological effects of ergosterol, which include antimicrobial, antioxidant, antimicrobial, anticancer, antidiabetic, anti-neurodegenerative, and other activities, have also been reported. This review aims to provide an overview of the available evidence regarding the pharmacological effects of ergosterol and its underlying mechanisms of action. Their potential benefits and applications are also discussed.

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