Journal
NATURE IMMUNOLOGY
Volume 17, Issue 10, Pages 1135-1136Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ni.3561
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Follicular helper T cells (T-FH cells) sequentially acquire the potential to secrete interleukin 21 (IL-21) and IL-4. The shift from secretion of IL-21 to that of IL-4 modifies the nature of the 'help' signals delivered by T-FH cells to germinal center (GC) B cells.
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