4.7 Editorial Material

Tcf1 and Lef1 pack their own HDAC

Journal

NATURE IMMUNOLOGY
Volume 17, Issue 6, Pages 615-616

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/ni.3469

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Funding

  1. NIGMS NIH HHS [T32 GM007308] Funding Source: Medline

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The transcription factors Tcf1 and Lef1 have intrinsic histone-deacetylase activity that is required for the repression of CD4(+) T cell-lineage genes in CD8(+) T cells.

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