4.7 Article

The evolution of innate lymphoid cells

Journal

NATURE IMMUNOLOGY
Volume 17, Issue 7, Pages 790-794

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/ni.3459

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Funding

  1. European Research Council (THINK Advanced Grant)
  2. Ligue Nationale contre le Cancer (Equipe Labellisee)
  3. INSERM
  4. CNRS
  5. Aix-Marseille University
  6. Institut Universitaire de France
  7. A*MIDEX
  8. Fondation pour la Recherche Medicale [AJE20150633331]
  9. Agence Nationale de Recherche (Immunodev)
  10. National Institute of Allergy and Infectious Diseases
  11. National Institute of General Medical Sciences of the US National Institutes of Health
  12. National Health and Medical Research Council of Australia
  13. Victorian State Government Operational Infrastructure Support
  14. Australian Government National Health and Medical Research Council of Australia Independent Research Institutes Infrastructure Support Scheme
  15. Australian Research Council

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Innate lymphoid cells (ILCs) are the most recently discovered group of immune cells. Understanding their biology poses many challenges. We discuss here the current knowledge on the appearance of ILC subsets during evolution and propose how the connection between ILCs and T cells contributes to the robustness of immunity and hence to the fitness of the hosts.

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